Gene signature predicting recurrence in oral squamous cell carcinoma is characterized by increased oxidative phosphorylation
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13328
Abstract: Although numerous studies have used systemic approaches to identify prognostic predictors in oral squamous cell carcinoma (OSCC), the effectiveness of these approaches has not been assessed clinically. Further, the mechanism underlying malignant behaviors in OSCC… read more here.
Keywords: cell carcinoma; oxidative phosphorylation; squamous cell; gene signature ... See more keywords
A 29‐gene signature associated with NOX2 discriminates acute myeloid leukemia prognosis and survival
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26477
Abstract: The molecular complexity displayed in acute myeloid leukemia (AML) hinders patient stratification and treatment decisions. Previous studies support the utility of using specific gene panels for this purpose. Focusing on two salient features of AML,… read more here.
Keywords: expression; acute myeloid; gene signature; myeloid leukemia ... See more keywords
Identification of a combined apoptosis and hypoxia gene signature for predicting prognosis and immune infiltration in breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer medicine"
DOI: 10.1002/cam4.4755
Abstract: BACKGROUND Breast cancer (BC) is the most common malignant tumor worldwide. Apoptosis and hypoxia are involved in the progression of BC, but reliable biomarkers for these have not been developed. We hope to explore a… read more here.
Keywords: prognosis; cancer; signature; gene ... See more keywords
Five genes as a novel signature for predicting the prognosis of patients with laryngeal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29535
Abstract: In this study, we purpose to investigate a novel five‐gene signature for predicting the prognosis of patients with laryngeal cancer. The laryngeal cancer datasets were obtained from The Cancer Genome Atlas (TCGA). Both univariate and… read more here.
Keywords: laryngeal cancer; prognosis; signature; cancer ... See more keywords
Identification of a novel cell cycle‐related gene signature predicting survival in patients with gastric cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27365
Abstract: Gastric cancer (GC) is one of the most fatal cancers in the world. Thousands of biomarkers have been explored that might be related to survival and prognosis via database mining. However, the prediction effect of… read more here.
Keywords: cancer; gene signature; gene; cell cycle ... See more keywords
Prognostic value of a gene signature in clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27700
Abstract: Renal cancer is a common urogenital system malignance. Novel biomarkers could provide more and more critical information on tumor features and patients’ prognosis. Here, we performed an integrated analysis on the discovery set and established… read more here.
Keywords: cell renal; renal cell; signature; gene signature ... See more keywords
Comprehensive analysis of HHV‐6 and HHV‐7‐related gene signature in prognosis and response to temozolomide of glioma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28285
Abstract: Human herpesvirus (HHV)‐6 and HHV‐7 have been detected in central nervous system and glioma tissue, while their exact role in glioma remains uncertain. Omics profiles and clinical information were downloaded from public databases, including The… read more here.
Keywords: temozolomide; hhv; hhv hhv; gene signature ... See more keywords
A breast cancer gene signature for indolent disease
Sign Up to like & getrecommendations! Published in 2017 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-017-4262-0
Abstract: PurposeEarly-stage hormone-receptor positive breast cancer is treated with endocrine therapy and the recommended duration of these treatments has increased over time. While endocrine therapy is considered less of a burden to patients compared to chemotherapy,… read more here.
Keywords: cancer; gene signature; breast cancer;
Patient-centered simulations to assess the usefulness of the 70-gene signature for adjuvant chemotherapy administration in early-stage breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-018-05107-6
Abstract: PurposeFrom the MINDACT trial, Cardoso et al. did not demonstrate a significant efficacy for adjuvant chemotherapy (CT) for women with early-stage breast cancer presenting high clinical and low genomic risks. Our objective was to assess… read more here.
Keywords: breast; stage breast; breast cancer; early stage ... See more keywords
Large-Scale Analysis Reveals Gene Signature for Survival Prediction in Primary Glioblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-02088-w
Abstract: Glioblastoma multiforme (GBM) is the most aggressive and common primary central nervous system tumour. Despite extensive therapy, GBM patients usually have poor prognosis with a median survival of 12–15 months. Novel molecular biomarkers that can… read more here.
Keywords: analysis; survival prediction; gene signature; gene ... See more keywords
A novel 4-gene signature model simultaneously predicting malignant risk of oral potentially malignant disorders and oral squamous cell carcinoma prognosis.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2021.105203
Abstract: OBJECTIVE Oral squamous cell carcinoma (OSCC) is often diagnosed at late stage with a poor prognosis. The study hereunder aimed to construct a multi-gene model to simultaneously promote early diagnosis of OSCC by evaluating malignant… read more here.
Keywords: malignant risk; risk; prognosis; model ... See more keywords