A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15932
Abstract: Predicting unanticipated harmful effects of chemicals and drug molecules is a difficult and costly task. Here we utilize a ‘big data compacting and data fusion’—concept to capture diverse adverse outcomes on cellular and organismal levels.… read more here.
Keywords: space; gene space; transcriptomics data; drug induced ... See more keywords
Assembly of the 373k gene space of the polyploid sugarcane genome reveals reservoirs of functional diversity in the world's leading biomass crop
Sign Up to like & getrecommendations! Published in 2019 at "GigaScience"
DOI: 10.1093/gigascience/giz129
Abstract: ABSTRACT Background Sugarcane cultivars are polyploid interspecific hybrids of giant genomes, typically with 10–13 sets of chromosomes from 2 Saccharum species. The ploidy, hybridity, and size of the genome, estimated to have >10 Gb, pose… read more here.
Keywords: diversity; gene space; sugarcane; genome ... See more keywords