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1
Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7321-7_11
Abstract: For the genetic alterations of NMDA receptor (NMDAR) properties like Ca2+-permeability or voltage-dependent gating in mice and for the experimental analysis of nonsense or missense mutations that were identified in human patients, single nucleotide mutations…
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Keywords:
gene targeted;
nmdar;
nmdar mutations;
targeting vector ... See more keywords
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2
Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2221060120
Abstract: Significance Amino acid substitutions within the cervid prion protein (PrP) can decrease susceptibility to chronic wasting disease, generally with more prominent effects in homozygous animals. Using novel gene-targeted mouse models expressing S138N reindeer/caribou PrP, we…
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Keywords:
gene targeted;
prion;
prp;
conversion ... See more keywords
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0
Published in 2017 at "International heart journal"
DOI: 10.1536/ihj.16-133
Abstract: Long QT syndrome (LQTS) has great genetic heterogeneity: more than 500 mutations have been described in several genes. Despite many advances, a genetic diagnosis still cannot be established in 25-30% of patients. The aim of…
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Keywords:
russian families;
gene targeted;
analysis;
targeted analysis ... See more keywords