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Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202200096
Abstract: As research on refractory Staphylococcus aureus‐related implant infection intensifies, certain challenges remain, including low antibiotic concentrations within infected areas, immune escape achieved by intracellular bacteria, myeloid‐derived suppressor cells (MDSCs) inducing regional immunosuppression, and recurrence of…
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Keywords:
multi mode;
antibacterial strategies;
mode antibacterial;
gene transfection ... See more keywords
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1
Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201800728
Abstract: Branched and dendrimeric cationic peptides have shown better transfection efficiency than linear peptides, owing to their superior capacity for inducing DNA condensation. We have designed and synthesized two analogously guanidinocarbonylpyrrole‐substituted (GCP‐substituted) branched cationic tripeptides that…
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Keywords:
transfection;
efficient gene;
branched tripeptide;
tripeptide anion ... See more keywords
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Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800359
Abstract: High transfection efficiency and superior cell imaging are required for cationic polymers-based gene delivery system to afford high therapeutic effect but its high toxicity and unstable cell imaging are easily ignored. In this study, cationic…
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Keywords:
transfection;
bsa;
gene transfection;
gene ... See more keywords
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Published in 2017 at "Pharmaceutical Research"
DOI: 10.1007/s11095-017-2328-7
Abstract: PurposeThis study aimed to further explore the mechanisms behind the ability of certain linear polyamidoamines (PAAs) to transfect cells with minimal cytotoxicity.MethodsThe transfection efficiency of DNA complexed with a PAA of a molecular weight over…
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Keywords:
transfection;
paa polyplexes;
gene transfection;
comparison gene ... See more keywords
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Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.120751
Abstract: Cell chirality has been demonstrated to be important for controlling cell functions. However, it is not clear how the chirality of the extracellular microenvironment regulates cell adhesion and cytoskeletal structures and therefore affects gene transfection.…
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Keywords:
chirality focal;
gene;
gene transfection;
focal adhesions ... See more keywords
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1
Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00331
Abstract: The relatively low transfection efficiency limits further application of polymeric gene carriers. It is imperative to exploit a universal and simple strategy to enhance the gene transfection efficiency of polymeric gene carriers. Herein, we prepared…
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Keywords:
polymeric gene;
gene transfection;
transfection efficiency;
gene ... See more keywords
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1
Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b20490
Abstract: Gene transfection has broad applications in bioengineering and biomedical fields. Although many gene carrier materials and transfection methods have been developed, it remains unclear how cell morphology including cell spreading and elongation affects gene transfection.…
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Keywords:
cell morphology;
cell;
gene transfection;
transfection ... See more keywords
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Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b20221
Abstract: Although electrospun nanofibers have been used to deliver functional genes into cells attached to the surface of the nanofibers, yet the controllable release of genes from nanofibers and subsequent gene transfection with high efficiency remain…
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Keywords:
high efficiency;
surface;
gene transfection;
transfection ... See more keywords
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Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.6b08393
Abstract: Suckerin proteins, recently discovered in the sucker ring teeth of squids, represent a family of promising structural biomacromolecules that can form supramolecular networks stabilized by nanoconfined β-sheets. Exploiting this feature as well as their specific…
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Keywords:
drug delivery;
gene;
gene transfection;
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Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b02977
Abstract: Combinatorially synthesized materials, especially cationic polymers (CPs), with gene transfection function hold great promise in nanotechnology. However, the main limitations of the existing CPs [such as polyethylenimine (PEI), poly-l-arginine, or polyamidoamine-based dendrimers] as gene transfection…
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Keywords:
gene transfection;
composed polyamines;
gene;
cationic polymers ... See more keywords
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Published in 2017 at "Drug Delivery"
DOI: 10.1080/10717544.2016.1250139
Abstract: Abstract In this study, stable nano-sized bubbles (nanobubbles [NBs]) were produced using the mechanical agitation method in the presence of perfluorocarbon gases. NBs made with perfluoropropane had a smaller size (around 400 nm) compared to that…
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Keywords:
transfection;
development mechanically;
gene transfection;
gene ... See more keywords