A general and practical sulfonylation of benzylic ammonium salts with sulfonyl hydrazides for the synthesis of sulfones
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.151975
Abstract: Abstract A practical and efficient approach adopting transition-metal-free cross-coupling of sulfonyl hydrazides with benzyl ammonium salts has been developed to synthesize benzyl sulfones using Cs2CO3 as base under mild conditions. The protocol employs stable and… read more here.
Keywords: ammonium salts; sulfonylation benzylic; sulfonyl hydrazides; general practical ... See more keywords
A general and practical Ni-catalyzed C-H perfluoroalkylation of (hetero)arenes.
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DOI: 10.1039/c9cc01971e
Abstract: A direct perfluoroalkylation of (hetero)arenes using the air- and moisture-stable complex (dppf)Ni(o-tol)Cl was developed (23 examples). The novel procedure allows for the synthesis of various fluorinated products and tolerates sensitive functional groups including aldehydes, free… read more here.
Keywords: hetero arenes; general practical; perfluoroalkylation hetero; practical catalyzed ... See more keywords
A three-component, general and practical route for diastereoselective synthesis of aza-spirocyclic pyrazolones via a decarboxylative annulation process
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DOI: 10.1039/d0nj05915c
Abstract: An efficient, general, and practical route for highly diastereoselective synthesis of aza-spirocyclic pyrazolones from easily available α-amino acids, aldehydes, and alkylidene pyrazolones by means of a decarboxylative annulation process is reported. This high-yielding reaction proceeds… read more here.
Keywords: diastereoselective synthesis; spirocyclic pyrazolones; general practical; aza spirocyclic ... See more keywords
General, Practical and Selective Oxidation Protocol for CF3S into CF3S(O) Group
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DOI: 10.3390/molecules24071249
Abstract: A simple and efficient protocol for the oxidation of trifluoromethyl, mono- and difluoromethyl sulfides to the corresponding sulfoxides without over-oxidation to sulfones, using TFPAA prepared in situ from trifluoroacetic acid and 15% H2O2 aqueous solution… read more here.
Keywords: oxidation; cf3s; practical selective; selective oxidation ... See more keywords