Optimizing and evaluating biomarker combinations as trial-level general surrogates.
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DOI: 10.1002/sim.7996
Abstract: We extend the method proposed in a recent work by the Authors for trial-level general surrogate evaluation to allow combinations of biomarkers and provide a procedure for finding the "best" combination of biomarkers based on… read more here.
Keywords: level general; biomarker; trial level; general surrogates ... See more keywords