LAUSR

On TCR binding predictors failing to generalize to unseen peptides

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2 Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1014256

Abstract: Several recent studies investigate TCR-peptide/-pMHC binding prediction using machine learning or deep learning approaches. Many of these methods achieve impressive results on test sets, which include peptide sequences that are also included in the training… read more here.

Keywords: negative samples; unseen peptides; tcr binding; generalize unseen ... See more keywords