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   Articles with "generalized pustular" as a keyword



Evaluation of a Case Series of Patients With Generalized Pustular Psoriasis in the United States.

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recommendations! Published in 2021 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2021.4640

Abstract: Importance Generalized pustular psoriasis (GPP) is a chronic, orphan disease with limited epidemiological data. Objective To describe the clinical characteristics, treatments, longitudinal disease course, and disease-specific health care utilization among patients with GPP across the… read more here.

Keywords: united states; case series; psoriasis; generalized pustular ... See more keywords

Understanding Flares in Patients With Generalized Pustular Psoriasis Documented in US Electronic Health Records

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recommendations! Published in 2022 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2022.3142

Abstract: Key Points Question What are the differences in treatment between patients with generalized pustular psoriasis (GPP) with flares and those without flares? Findings In this cohort study comprising 1535 patients with GPP, with 271 of… read more here.

Keywords: flares patients; patients generalized; generalized pustular; understanding flares ... See more keywords

Transcriptomic landscape of generalized pustular psoriasis before and after acitretin/glucocorticoids treatment

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recommendations! Published in 2025 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-025-01931-5

Abstract: Generalized pustular psoriasis (GPP) is a rare and severe subtype of psoriasis, characterized by sterile pustules on the skin surface. Acitretin is currently one of the first-line treatments for GPP, while glucocorticoids are commonly used… read more here.

Keywords: treatment; acitretin glucocorticoids; generalized pustular; pustular psoriasis ... See more keywords

Current Treatments for Generalized Pustular Psoriasis: A Narrative Summary of a Systematic Literature Search

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recommendations! Published in 2024 at "Dermatology and Therapy"

DOI: 10.1007/s13555-024-01230-z

Abstract: Generalized pustular psoriasis (GPP) is a rare, chronic and potentially life-threatening autoinflammatory skin disease characterized by widespread eruption of sterile pustules, with or without systemic inflammation. GPP can significantly reduce patients’ quality of life (QoL).… read more here.

Keywords: treatment; gpp; generalized pustular; literature ... See more keywords

Impact of Generalized Pustular Psoriasis from the Perspective of People Living with the Condition: Results of an Online Survey

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recommendations! Published in 2022 at "American Journal of Clinical Dermatology"

DOI: 10.1007/s40257-021-00663-y

Abstract: Generalized pustular psoriasis (GPP) is a rare disease characterized by episodic worsening (flares). Knowledge of the burden of GPP and the experience of affected individuals is limited. To conduct a survey of people living with… read more here.

Keywords: survey; people living; generalized pustular; pustular psoriasis ... See more keywords
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Real-world single-center experience with ten cases of generalized pustular psoriasis successfully treated with ixekizumab.

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recommendations! Published in 2019 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2019.09.040

Abstract: Generalized pustular psoriasis, a severe systemic inflammatory disease accompanied by erythema and pustules on the entire body, is so rare that data on the treatment for it is quite limited. Our ten cases revealed that… read more here.

Keywords: real world; generalized pustular; world single; pustular psoriasis ... See more keywords
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Treatments and outcomes of generalized pustular psoriasis: a cohort of 1516 patients in a nationwide inpatient database in Japan.

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recommendations! Published in 2021 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2021.06.008

Abstract: BACKGROUND Because generalized pustular psoriasis (GPP) is uncommon, there are few studies reporting treatments and outcomes for large numbers of patients. OBJECTIVE To report treatments and outcomes in a large cohort of hospitalized patients with… read more here.

Keywords: 1516 patients; generalized pustular; inpatient database; pustular psoriasis ... See more keywords
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Acute generalized pustular psoriasis exacerbated by the COVID-19 vaccine

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recommendations! Published in 2021 at "JAAD Case Reports"

DOI: 10.1016/j.jdcr.2021.08.035

Abstract: CASE REPORT A man in his 40s with morbid obesity, hypertension, depression/anxiety, and psoriasis presented with an acute, rapidly progressive skin eruption. His preexisting psoriasis had been present for years, with minimally symptomatic transient plaques… read more here.

Keywords: generalized pustular; acute generalized; psoriasis; vaccine ... See more keywords

Efficacy of adalimumab in pediatric generalized pustular psoriasis: case series and literature review

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recommendations! Published in 2022 at "Journal of Dermatological Treatment"

DOI: 10.1080/09546634.2022.2089327

Abstract: Abstract Background Generalized pustular psoriasis (GPP) is a rare, severe, and sometimes fatal form of childhood psoriasis. The first line therapies include acitretin, cyclosporin A, and methotrexate which take effect slowly and have varying long-term… read more here.

Keywords: generalized pustular; efficacy; pustular psoriasis; literature ... See more keywords

Clinical course and disease burden of patients with generalized pustular psoriasis in Portugal: a multicenter retrospective cohort study

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recommendations! Published in 2024 at "Journal of Dermatological Treatment"

DOI: 10.1080/09546634.2024.2345728

Abstract: Abstract Objectives Generalized pustular psoriasis (GPP) is a rare, life-threatening skin inflammatory disorder. This study aimed to describe the disease course, treatment strategies, and healthcare utilization among patients with GPP in Portugal. Methods This multicentric,… read more here.

Keywords: disease; course; generalized pustular; pustular psoriasis ... See more keywords

Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion

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recommendations! Published in 2022 at "Expert Review of Clinical Immunology"

DOI: 10.1080/1744666x.2022.2116003

Abstract: ABSTRACT Introduction Generalized pustular psoriasis (GPP) is a rare, severe, clinically heterogeneous disease characterized by flares of widespread, noninfectious, macroscopically visible pustules that occur with or without systemic inflammation, and are associated with significant morbidity… read more here.

Keywords: disease; generalized pustular; psoriasis vulgaris; gpp ... See more keywords