Long‐term open‐label perampanel: Generalized tonic–clonic seizures in idiopathic generalized epilepsy
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DOI: 10.1002/epi4.12602
Abstract: Assess the longer‐term efficacy and safety of adjunctive perampanel (up to 12 mg/day) in patients aged ≥12 years with generalized tonic–clonic (GTC) seizures from the Open‐label Extension (OLEx) Phase of Study 332 to determine whether responses obtained… read more here.
Keywords: long term; generalized tonic; term; tonic clonic ... See more keywords
T01. Role of hypothalamic hamartoma in non-gelastic seizures: An exploration of the brain network
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2018.04.002
Abstract: Introduction Patients having a hypothalamic hamartoma frequently present epileptic attacks of laughter, and they later experience multiple additional seizure types. Because of these types of seizures, hypothalamic hamartomas are considered to be a type of… read more here.
Keywords: non gelastic; hamartoma; gelastic seizures; hypothalamic hamartoma ... See more keywords
Mutational screening of GABRG2 gene in Pakistani population of Punjab with generalized tonic clonic seizures and children with childhood absence epilepsy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Chinese Medical Association"
DOI: 10.1016/j.jcma.2018.05.001
Abstract: Background: Epilepsy is a multifaceted and multistep disorder that disrupts the proper functioning of neurons. It is becoming increasingly clear that the responsiveness of neurons depends on the appropriate trafficking of ions across the channels… read more here.
Keywords: epilepsy; gabrg2; childhood absence; absence epilepsy ... See more keywords
Anticonvulsant drugs for generalized tonic-clonic epilepsy
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1328499
Abstract: ABSTRACT Introduction: Primary generalized tonic clonic seizures (pGTCS) are still linked to major concerns for the clinic and hazards for patients suffering from idiopathic generalized epilepsy (IGE), so a quick search of the most effective… read more here.
Keywords: epilepsy; tonic clonic; first choice; valproic acid ... See more keywords
Wilson’s Disease Presenting with Generalized Tonic-Clonic Seizure and Cerebellar Dysfunction
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DOI: 10.2147/imcrj.s320639
Abstract: Abstract Wilson’s disease (WD) is a rare inherited impaired copper metabolism with diverse clinical pictures dominated by hepatic and neurologic manifestations. We report the case of a 14-year-old female patient who attended the Department of… read more here.
Keywords: tonic clonic; cerebellar dysfunction; seizure cerebellar; clonic seizure ... See more keywords
Multimodal Data and Machine Learning for Detecting Specific Biomarkers in Pediatric Epilepsy Patients With Generalized Tonic-Clonic Seizures
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2018.01038
Abstract: Previous neuroimaging studies of epilepsy with generalized tonic-clonic seizures (GTCS) focus mainly on adults. However, the neural mechanisms that underline this type of epilepsy remain unclear, especially for children. The aim of the present study… read more here.
Keywords: epilepsy; tonic clonic; right thalamus; clonic seizures ... See more keywords
Amplitude of Low-Frequency Fluctuation With Different Clinical Outcomes in Patients With Generalized Tonic–Clonic Seizures
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.847366
Abstract: Background Generalized tonic–clonic seizures (GTCS) are associated with significant disability and sudden unexpected death when they cannot be controlled. We aimed to explore the underlying neural substrate of the different responses to antiseizure drugs between… read more here.
Keywords: generalized tonic; clonic seizures; gyrus; amplitude low ... See more keywords
EEG Network Analysis in Epilepsy with Generalized Tonic–Clonic Seizures Alone
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DOI: 10.3390/brainsci12111574
Abstract: Many contradictory theories regarding epileptogenesis in idiopathic generalized epilepsy have been proposed. This study aims to define the network that takes part in the formation of the spike-wave discharges in patients with generalized tonic–clonic seizures… read more here.
Keywords: generalized tonic; network; clonic seizures; analysis ... See more keywords