Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.
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DOI: 10.1016/j.cels.2017.08.002
Abstract: The systematic sequencing of the cancer genome has led to the identification of numerous genetic alterations in cancer. However, a deeper understanding of the functional consequences of these alterations is necessary to guide appropriate therapeutic strategies. Here,… read more here.
Keywords: cellular states; transcriptional signatures; generate maps; decomposing oncogenic ... See more keywords