Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.7b00018
Abstract: The remodeling of active sites to generate novel biocatalysts is an attractive and challenging task. We developed a stepwise loop insertion strategy (StLois), in which randomized residue pairs are inserted into active site loops. The… read more here.
Keywords: generate novel; stepwise loop; active site; site ... See more keywords
Corrigendum: Using Machine Learning to Generate Novel Hypotheses: Increasing Optimism About COVID-19 Makes People Less Willing to Justify Unethical Behaviors
Sign Up to like & getrecommendations! Published in 2021 at "Psychological Science"
DOI: 10.1177/09567976211004118
Abstract: A reader pointed out that Sheetal et al.’s interpretation of an article cited in the General Discussion was inconsistent with the claims made in that article. This Corrigendum is correcting that passage, altering a few… read more here.
Keywords: generate novel; machine learning; learning generate; using machine ... See more keywords