N-Isocyanodialkylamines generated in situ for the Joullié–Ugi reaction with indolenines
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DOI: 10.1016/j.tetlet.2018.08.025
Abstract: Abstract N-Isocyanodialkylamines are rare isocyanide surrogates for the Ugi-type reactions. To avoid problems with instability and the obnoxious smell of these reagents, we optimized and employed a convenient protocol for in situ dehydration of N,N-dialkyl-N′-formyl… read more here.
Keywords: generated situ; joulli ugi; situ joulli; isocyanodialkylamines generated ... See more keywords
Catalytic Enantioselective Cyclopropylalkynylation of Aldimines Generated In Situ from α-Amido Sulfones
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DOI: 10.3390/molecules27123763
Abstract: A convenient procedure of synthesis of N-carbamoyl-protected propargylic amines substituted with a cyclopropyl group from α-amido sulfones and cyclopropylacetylene is described. The reaction is catalyzed by a chiral BINOL-type zinc complex and provides the corresponding… read more here.
Keywords: cyclopropylalkynylation aldimines; catalytic enantioselective; generated situ; amido sulfones ... See more keywords