Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples
Sign Up to like & getrecommendations! Published in 2022 at "Cell Chemical Biology"
DOI: 10.1016/j.chembiol.2022.01.009
Abstract: Coagulation cofactors profoundly regulate hemostasis and are appealing targets for anticoagulants. However, targeting such proteins has been challenging because they lack an active site. To address this, we isolate an RNA aptamer termed T18.3 that… read more here.
Keywords: anticoagulant aptamer; aptamer targets; generation anticoagulant; anticoagulant activity ... See more keywords
Long-term trends of second generation anticoagulant rodenticides (SGARs) show widespread contamination of a bird-eating predator, the Eurasian Sparrowhawk (Accipiter nisus) in Britain.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.2139/ssrn.4144377
Abstract: Second generation anticoagulant rodenticides (SGARs) are widely used to control rodents around the world. However, contamination by SGARs is detectable in many non-target species, particularly carnivorous mammals or birds-of-prey that hunt or scavenge on poisoned… read more here.
Keywords: britain; second generation; contamination; bird eating ... See more keywords