Association of First- vs. Second-Generation Antipsychotics with Lipid Abnormalities in Individuals with Severe Mental Illness: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-019-00751-2
Abstract: Background and ObjectiveIndividuals with severe mental illness experience increased morbidity and mortality as a result of metabolic problems that may partly be related to the adverse effects of antipsychotics. Compared with first-generation antipsychotics, second-generation antipsychotics collectively… read more here.
Keywords: first generation; severe mental; generation; second generation ... See more keywords
Metabolic outcomes of Red yeast rice administration in patients treated with second-generation antipsychotics
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.02.385
Abstract: Rationale Second-generation antipsychotics (SGAs) are notoriously associated with a wide range of metabolic adverse effects, and their chronic use is related with an increased risk for the development of metabolic syndrome (MS). The nutraceutical approach… read more here.
Keywords: second generation; red yeast; generation antipsychotics; yeast rice ... See more keywords
Systematic Review and Network Meta-analysis: Efficacy and Safety of Second-Generation Antipsychotics in Youths With Bipolar Depression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Academy of Child and Adolescent Psychiatry"
DOI: 10.1016/j.jaac.2021.03.021
Abstract: OBJECTIVE To assess the relative efficacy and safety of second-generation antipsychotics for treating major depressive episodes in youths with bipolar disorder. METHOD A systematic literature review using PRISMA guidelines and network meta-analysis (NMA) of randomized… read more here.
Keywords: generation antipsychotics; efficacy; bipolar depression; second generation ... See more keywords
Efficacy and acceptability of second-generation antipsychotics with antidepressants in unipolar depression augmentation: a systematic review and network meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Psychological Medicine"
DOI: 10.1017/s0033291722001246
Abstract: Abstract Pharmacological treatment of major depressive disorder is often inefficient, and multiple strategies are used for inadequate response to antidepressants. Second-generation antipsychotics are used as augmentation measures in clinical practice; evidence of their efficacy and… read more here.
Keywords: acceptability; second generation; generation antipsychotics; efficacy ... See more keywords
Comparing the efficacy of aripiprazole as an add-on to valproate with other second-generation antipsychotics in acute mania symptoms in manic patients in Iran
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Psychiatry in Clinical Practice"
DOI: 10.1080/13651501.2022.2030758
Abstract: Abstract Background Given the great importance of treating patients with bipolar disorder, the aim of this study was to compare the efficacy of aripiprazole with other second-generation antipsychotics in relieving acute symptoms of mania. Materials… read more here.
Keywords: second generation; generation antipsychotics; patients bipolar; bipolar disorder ... See more keywords
The incidence and economic burden of extrapyramidal symptoms in patients with schizophrenia treated with second generation antipsychotics in a Medicaid population.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical economics"
DOI: 10.1080/13696998.2021.2019501
Abstract: BACKGROUND Extrapyramidal symptoms (EPS) are common side effects of second generation antipsychotics (SGA), they can negatively impact patient quality of life, and are associated with increased morbidity and mortality. This study examined the incidence and… read more here.
Keywords: generation antipsychotics; patients schizophrenia; second generation; extrapyramidal symptoms ... See more keywords
Practitioners' Perspective on Metabolic Monitoring of Second-Generation Antipsychotics: Existing Gaps in Knowledge, Barriers to Monitoring, and Strategies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of child and adolescent psychopharmacology"
DOI: 10.1089/cap.2022.0021
Abstract: Introduction: Prescription of second-generation antipsychotics (SGAs) in youth is rapidly increasing globally and in Australia. Lack of timely metabolic monitoring for potential adverse effects puts youth at greater risk for lifelong adverse health impact. Metabolic… read more here.
Keywords: metabolic monitoring; second generation; generation antipsychotics; barriers monitoring ... See more keywords
T207. METABOLIC ADVERSE EFFECTS OF OFF-LABEL USE OF SECOND-GENERATION ANTIPSYCHOTICS IN THE ADULT POPULATION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbaa029.767
Abstract: Abstract Background Second generation antipsychotics (SGAs) are approved by the US Food and Drug Administration (FDA) for the treatment of schizophrenia, bipolar disorder and treatment refractory depression. Since the late 1990’s, prescription of antipsychotics has… read more here.
Keywords: use; metabolic adverse; adverse effects; second generation ... See more keywords
Long-acting injectable second-generation antipsychotics in first-episode psychosis: a narrative review
Sign Up to like & getrecommendations! Published in 2019 at "International Clinical Psychopharmacology"
DOI: 10.1097/yic.0000000000000249
Abstract: Long-acting injectable (LAI) antipsychotics could be a favorable option of treatment and have some advantages over oral medications. The aim of this study was to review the published data on the use of LAI formulation… read more here.
Keywords: first episode; acting injectable; generation antipsychotics; episode psychosis ... See more keywords
Assessment of cardiovascular risk in an Italian psychiatric outpatient sample: A chart review of patients treated with second‐generation antipsychotics
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Mental Health Nursing"
DOI: 10.1111/inm.12407
Abstract: Despite the call by the scientific community for a systematic monitoring of physical health in people with psychiatric illnesses, national and international audits have reported poor quality of cardiovascular risk assessments and management in this… read more here.
Keywords: cardiovascular risk; health; second generation; outpatient sample ... See more keywords
Off‐Label Prescribing of Second‐Generation Antipsychotics to Elderly Veterans with Posttraumatic Stress Disorder and Dementia
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DOI: 10.1111/jgs.14897
Abstract: To determine whether elderly veterans with posttraumatic stress disorder (PTSD) and dementia are more likely to be prescribed second‐generation antipsychotics (SGAs) than those with PTSD alone. read more here.
Keywords: stress disorder; posttraumatic stress; generation antipsychotics; veterans posttraumatic ... See more keywords