Sensitive measurement of clinically relevant factor VIII levels in thrombin generation assays requires presence of factor XIa.
Sign Up to like & getrecommendations! Published in 2023 at "Thrombosis and haemostasis"
DOI: 10.1055/a-2101-7961
Abstract: BACKGROUND Hemophilia A (HA) is characterized by decreased or absent FVIII. Current FVIII assays are based on clotting time and only provide information about the initiation of coagulation. In contrast, thrombin generation assays (TGA) can… read more here.
Keywords: thrombin generation; fviii; generation; generation assays ... See more keywords
Parathyroid hormone reference intervals in adults using second- and third-generation assays
Sign Up to like & getrecommendations! Published in 2023 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2164517
Abstract: Abstract Parathyroid hormone (PTH) is a routine biochemical analysis, and it varies whether a second- or third-generation assay is used. Information on the levels obtained with different assays and evidence to substantiate local assay-specific reference… read more here.
Keywords: third generation; generation; generation assays; second third ... See more keywords
Clinical use of thrombin generation assays
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15538
Abstract: Determining patient's coagulation profile, i.e. detecting a bleeding tendency or the opposite, a thrombotic risk, is crucial for clinicians in many situations. Routine coagulation assays and even more specialized tests may not allow a relevant… read more here.
Keywords: clinical use; generation assays; generation; use thrombin ... See more keywords