Generation and Characterization of Site‐Specifically Mono‐Ubiquitylated p53
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202100659
Abstract: The tumor suppressor p53 is regulated by various posttranslational modifications including different types of ubiquitylation, which exert distinct effects on p53. While modification by ubiquitin chains targets p53 for degradation, attachment of single ubiquitin moieties… read more here.
Keywords: mono ubiquitylated; site specifically; specifically mono; generation characterization ... See more keywords
Generation and characterization of a Ddx4‐iCre transgenic line for deletion in the germline beginning at genital ridge colonization
Sign Up to like & getrecommendations! Published in 2023 at "genesis"
DOI: 10.1002/dvg.23511
Abstract: Germline‐specific Cre lines are useful for analyses of primordial germ cell, spermatogonial and oogonial development, but also for whole‐body deletions when transmitted through subsequent generations. Several germ cell specific Cre mouse strains exist, with various… read more here.
Keywords: icre; deletion; germline; ddx4 ... See more keywords
Generation, characterization, and protective ability of mouse monoclonal antibodies against the HA of A (H1N1) influenza virus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27584
Abstract: Influenza virus infections pose a continuous threat to human health. Although vaccines function as a preventive and protective tool, they may not be effective due to antigen drift or an inaccurate prediction of epidemic strains.… read more here.
Keywords: virus; three mabs; generation characterization; characterization protective ... See more keywords
Generation and characterization of humanized synergistic neutralizing antibodies against SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27801
Abstract: The emerging coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is the causative agent of coronavirus disease 2019 (COVID‐19), which has become a severe threat to global public health and local economies. In this study,… read more here.
Keywords: characterization humanized; synergistic neutralizing; humanized synergistic; generation characterization ... See more keywords
Generation and Characterization of Cell-Derived Microvesicles from HUVECs
Sign Up to like & getrecommendations! Published in 2018 at "BioNanoScience"
DOI: 10.1007/s12668-017-0438-7
Abstract: Microvesicles (MVs) are of great interest for the biomedical field as novel diagnostics biomarkers. MV research, however, is still impaired by the lack of standardization of the analysis methods. In this study, our goals were… read more here.
Keywords: characterization cell; cell derived; generation; generation characterization ... See more keywords
Generation and characterization of carbon fiber microstructures by atomistic simulations
Sign Up to like & getrecommendations! Published in 2019 at "Carbon"
DOI: 10.1016/j.carbon.2019.06.014
Abstract: Abstract A clear understanding of carbon fiber (CF) microstructure is necessary for the development of high strength CFs. Here, we present an atomistic approach for generating and characterizing realistic microstructures of CFs. Large-scale reactive molecular… read more here.
Keywords: carbon; generation characterization; carbon fiber;
Generation and characterization of a potent fully human monoclonal antibody against the interleukin‐23 receptor
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.03.036
Abstract: ABSTRACT Interleukin (IL)‐12 and IL‐23 share a common subunit (p40) and function in T‐helper (Th) 1 and Th17 immunity, respectively. Anti‐IL‐12/23p40 and specific anti‐IL‐23 antibodies are currently in clinical use for psoriasis and undergoing trials… read more here.
Keywords: human monoclonal; antibody; fully human; generation characterization ... See more keywords
Generation and characterization of eight human-derived iPSC lines from affected and unaffected THAP1 mutation carriers.
Sign Up to like & getrecommendations! Published in 2018 at "Stem cell research"
DOI: 10.1016/j.scr.2018.09.018
Abstract: Mutations in THAP1 (THAP domain-containing apoptosis-associated protein 1) cause a form of early-onset, isolated dystonia (DYT-THAP1, aka DYT6). Here, we describe the generation of eight human induced pluripotent stem cell (iPSC) lines of manifesting and… read more here.
Keywords: eight human; characterization eight; generation characterization; ipsc lines ... See more keywords
Generation and characterization of human induced pluripotent stem cells (iPSCs) from three individuals without age-related macular degeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cell research"
DOI: 10.1016/j.scr.2022.102670
Abstract: Age-related macular degeneration (AMD) is a major cause of vision loss among the elderly in the Western world. AMD is multifactorial eye disease with a strong genetic contribution. Here, we report the generation and characterization… read more here.
Keywords: age; age related; stem; macular degeneration ... See more keywords
Generation and Characterization of Recombinant Antibody-like ADP-Ribose Binding Proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00670
Abstract: ADP-ribosylation is an enzyme-catalyzed post-translational modification of proteins in which the ADP-ribose (ADPR) moiety of NAD+ is transferred to a specific amino acid in a substrate protein. The biological functions of ADP-ribosylation are numerous and… read more here.
Keywords: biochemistry; recombinant antibody; generation characterization; biology ... See more keywords
Photochemical Generation and Characterization of Di-tert-butylsilylene (SitBu2) in Solution
Sign Up to like & getrecommendations! Published in 2019 at "Organometallics"
DOI: 10.1021/acs.organomet.8b00902
Abstract: Di-tert-butylsilylene (SitBu2) has been detected directly in solution and its reactivity characterized by laser flash photolysis methods. Laser photolysis of 7,7-di-tert-butyl-7-silabicyclo[4.1.0]heptane (5) affords a transient product that exhibits λmax ≈ 520 nm and decays on… read more here.
Keywords: photochemical generation; butylsilylene sitbu2; tert butylsilylene; characterization tert ... See more keywords