Generation of Functional Thyroid Tissue Using 3D-Based Culture of Embryonic Stem Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6949-4_7
Abstract: During the last decade three-dimensional (3D) cultures of pluripotent stem cells have been intensively used to understand morphogenesis and molecular signaling important for the embryonic development of many tissues. In addition, pluripotent stem cells have… read more here.
Keywords: generation functional; thyroid tissue; stem; functional thyroid ... See more keywords
Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system
Sign Up to like & getrecommendations! Published in 2017 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-017-0015-1
Abstract: Generation of functional spermatids from human spermatogonial stem cells (SSCs) in vitro is of utmost importance for uncovering mechanisms underlying human germ cell development and treating infertility. Here we report a three-dimensional-induced (3D-I) system by… read more here.
Keywords: generation functional; human sscs; system; spermatids human ... See more keywords
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18031-5
Abstract: Our understanding of the spatiotemporal regulation of cardiogenesis is hindered by the difficulties in modeling this complex organ currently by in vitro models. Here we develop a method to generate heart organoids from mouse embryonic… read more here.
Keywords: generation functional; fgf4; heart organoids; heart ... See more keywords
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2017 at "mAbs"
DOI: 10.1080/19420862.2017.1353853
Abstract: ABSTRACT Deficiency of interleukin (IL)-36 receptor antagonist (DITRA) syndrome is a rare autosomal recessive disease caused by mutations in IL36RN. IL-36R is a cell surface receptor and a member of the IL1R family that is… read more here.
Keywords: generation functional; mouse 36r; 36r signaling; anti human ... See more keywords
Generation of functional fat organoid from rat superficial fascia
Sign Up to like & getrecommendations! Published in 2022 at "Adipocyte"
DOI: 10.1080/21623945.2022.2072446
Abstract: ABSTRACT The organoid is a 3D cell architecture formed by self-organized tissues or cells in vitro with similar cell types, histological structures, and biological functions of the native organ. Depending on the unique organ structures… read more here.
Keywords: fascia; superficial fascia; fat organoids; functional fat ... See more keywords
Rapid generation of functional engineered 3D human neuronal assemblies: network dynamics evaluated by micro-electrodes arrays
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neural Engineering"
DOI: 10.1088/1741-2552/ac3e02
Abstract: Objective. In this work we adapted a protocol for the fast generation of human neurons to build 3D neuronal networks with controlled structure and cell composition suitable for systematic electrophysiological investigations. Approach. We used biocompatible… read more here.
Keywords: rapid generation; generation functional; neuronal networks; functional engineered ... See more keywords
Information generation as a functional basis of consciousness
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience of Consciousness"
DOI: 10.1093/nc/niz016
Abstract: Abstract What is the biological advantage of having consciousness? Functions of consciousness have been elusive due to the subjective nature of consciousness and ample empirical evidence showing the presence of many nonconscious cognitive performances in… read more here.
Keywords: consciousness information; information; information generation; generation functional ... See more keywords