Large‐Scale Ex Vivo Generation of Human Red Blood Cells from Cord Blood CD34+ Cells
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.17-0057
Abstract: The ex vivo generation of human red blood cells on a large scale from hematopoietic stem and progenitor cells has been considered as a potential method to overcome blood supply shortages. Here, we report that… read more here.
Keywords: medicine; cd34; vivo generation; generation human ... See more keywords
Generation of human iPSCs from urine derived cells of a non-affected control subject.
Sign Up to like & getrecommendations! Published in 2017 at "Stem cell research"
DOI: 10.1016/j.scr.2016.12.008
Abstract: We have generated a human induced pluripotent stem cell (iPSC) line under feeder-free culture conditions using the urine derived cells (UCs) collected from non-affected control subjects to use as a comparison group for the iPSC… read more here.
Keywords: affected control; generation human; non affected; derived cells ... See more keywords
Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101524
Abstract: SLC26A4 is the second most frequent gene implicated in congenital hearing loss after GJB2 mutations. Here, we report the generation of induced pluripotent stem cells (iPSCs), from a patient who was carrying a homozygous c.919-2A>G… read more here.
Keywords: cell line; human ips; patient carrying; ips cell ... See more keywords
Generation of human iPS cell line CBTCi001-A from dermal fibroblasts obtained from a healthy donor.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101630
Abstract: Human-induced pluripotent stem cell (hiPSC) CBTCi001-A line was generated from a healthy 30-year old male dermal fibroblasts using non-integrative reprogramming method using episomal-based plasmids expressing OCT4, SOX2, KLF4, and MYCL. Characterization of CBTCi001-A was confirmed… read more here.
Keywords: line; human ips; ips cell; cbtci001 ... See more keywords
Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2017.01.014
Abstract: Summary Astrocytes, due to the proximity to neuronal lineage and capability to proliferate, are ideal starting cells to regenerate neurons. Human fetal astrocytes have been successfully converted into neuronal cells by small molecules, which offered… read more here.
Keywords: neuronal cells; small molecules; astrocytes small; adult astrocytes ... See more keywords
Direct Generation of Human Cortical Organoids from Primary Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Stem cells and development"
DOI: 10.1089/scd.2018.0112
Abstract: The study of variations in human neurodevelopment and cognition is limited by the availability of experimental models. While animal models only partially recapitulate the human brain development, genetics, and heterogeneity, human-induced pluripotent stem cells can… read more here.
Keywords: direct generation; human cortical; generation human; cortical organoids ... See more keywords
A next-generation human genome sequence.
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abo5367
Abstract: A near-complete sequence outlines a path for a more inclusive reference. read more here.
Keywords: human genome; generation human; next generation; genome sequence ... See more keywords
From Mice to Men: Generation of Human Blastocyst-Like Structures In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.838356
Abstract: Advances in the field of stem cell-based models have in recent years lead to the development of blastocyst-like structures termed blastoids. Blastoids can be used to study key events in mammalian pre-implantation development, as they… read more here.
Keywords: blastocyst like; like structures; generation human; men generation ... See more keywords
Fibrin and Marine-Derived Agaroses for the Generation of Human Bioartificial Tissues: An Ex Vivo and In Vivo Study
Sign Up to like & getrecommendations! Published in 2023 at "Marine Drugs"
DOI: 10.3390/md21030187
Abstract: Development of an ideal biomaterial for clinical use is one of the main objectives of current research in tissue engineering. Marine-origin polysaccharides, in particular agaroses, have been widely explored as scaffolds for tissue engineering. We… read more here.
Keywords: biomechanical properties; generation human; tissue engineering; marine ... See more keywords