The time for next-generation molecular genetic diagnostics in nephrology is now!
Sign Up to like & getrecommendations! Published in 2018 at "Kidney international"
DOI: 10.1016/j.kint.2018.03.025
Abstract: Global and disease-group genetic testing is replacing single-gene molecular diagnostics. Bullich et al. demonstrate that gene panel analysis can result in a high yield of genetic diagnoses in cystic and familial glomerular populations. As the complexity… read more here.
Keywords: nephrology; time next; molecular genetic; genetic diagnostics ... See more keywords
Next-Generation Molecular Surveillance of TriTryp Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in parasitology"
DOI: 10.1016/j.pt.2020.01.008
Abstract: Elimination programs targeting TriTryp diseases (Leishmaniasis, Chagas' disease, human African trypanosomiasis) significantly reduced the number of cases. Continued surveillance is crucial to sustain this progress, but parasite molecular surveillance by genotyping is currently lacking. We… read more here.
Keywords: surveillance; molecular surveillance; tritryp diseases; generation molecular ... See more keywords
Generation and molecular marker and cytological characterization of wheat-Secale strictum subsp. anatolicum derivatives.
Sign Up to like & getrecommendations! Published in 2020 at "Genome"
DOI: 10.1139/gen-2020-0060
Abstract: Cereal rye and its wild forms are important sources of genetic diversity for wheat breeding due to their resistances to biotic and abiotic stresses. Secale strictum subsp. anatolicum (Boiss.) K.Hammer (SSA) is a weedy relative… read more here.
Keywords: wheat; strictum subsp; subsp anatolicum; generation molecular ... See more keywords
Pediatric Sarcomas: The Next Generation of Molecular Studies
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14102515
Abstract: Simple Summary There has been an incredible amount of discovery in pediatric sarcomas, but much remains to be accomplished. Clinical challenges include diagnostic heterogeneity and the poor outcome of patients with high risk, metastatic, and… read more here.
Keywords: sarcomas next; molecular studies; cell; generation molecular ... See more keywords
Next-Generation Molecular Investigations in Lysosomal Diseases: Clinical Integration of a Comprehensive Targeted Panel
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11020294
Abstract: Diagnosis of lysosomal disorders (LDs) may be hampered by their clinical heterogeneity, phenotypic overlap, and variable age at onset. Conventional biological diagnostic procedures are based on a series of sequential investigations and require multiple sampling.… read more here.
Keywords: investigations lysosomal; generation molecular; panel; molecular investigations ... See more keywords