Articles with "generation p53" as a keyword



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Prolonged Idasanutlin (RG7388) Treatment Leads to the Generation of p53-Mutated Cells

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Published in 2018 at "Cancers"

DOI: 10.3390/cancers10110396

Abstract: The protein p53 protects the organism against carcinogenic events by the induction of cell cycle arrest and DNA repair program upon DNA damage. Virtually all cancers inactivate p53 either by mutations/deletions of the TP53 gene… read more here.

Keywords: idasanutlin rg7388; generation p53; treatment; p53 mutated ... See more keywords