Generation of a Phage Display Chicken Single-Chain Variable Fragment Library.
Sign Up to like & getrecommendations! Published in 2024 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot108213
Abstract: Phage-displayed antibody fragment libraries can be constructed using essentially any species that is easily immunized, as long as the immunoglobulin variable region gene sequences are known. This protocol describes the procedures for the generation of… read more here.
Keywords: chain variable; phage; single chain; generation phage ... See more keywords
PDL1Binder: Identifying programmed cell death ligand 1 binding peptides by incorporating next-generation phage display data and different peptide descriptors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.928774
Abstract: Monoclonal antibody drugs targeting the PD-1/PD-L1 pathway have showed efficacy in the treatment of cancer patients, however, they have many intrinsic limitations and inevitable drawbacks. Peptide inhibitors as alternatives might compensate for the drawbacks of… read more here.
Keywords: different peptide; next generation; binding peptides; generation phage ... See more keywords