Strategies for Development of a Next-Generation Protein Sequencing Platform.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2019.09.005
Abstract: Proteomic analysis can be a critical bottleneck in cellular characterization. The current paradigm relies primarily on mass spectrometry of peptides and affinity reagents (i.e., antibodies), both of which require a priori knowledge of the sample.… read more here.
Keywords: protein; generation protein; strategies development; protein sequencing ... See more keywords
Monobodies as possible next-generation protein therapeutics - a perspective.
Sign Up to like & getrecommendations! Published in 2017 at "Swiss medical weekly"
DOI: 10.4414/smw.2017.14545
Abstract: Over the past two decades, hundreds of new somatic mutations have been identified in tumours, and a few dozen novel cancer therapeutics that selectively target these mutated oncoproteins have entered clinical practice. This development has… read more here.
Keywords: protein; monobodies possible; possible next; generation protein ... See more keywords