Generation of Targeted Point Mutations in Rice by a Modified CRISPR/Cas9 System.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular plant"
DOI: 10.1016/j.molp.2016.12.001
Abstract: CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated Cas9 endonuclease)-mediated genome editing has revolutionized biological research and crop improvement because of its specificity, simplicity, and versatility (reviewed in Komor et al., 2016a). Editing a gene by… read more here.
Keywords: targeted point; point mutations; crispr cas9; generation targeted ... See more keywords
Next-generation targeted sequencing (NGTS) investigating CDK4 as a prognostic driver in pure invasive lobular breast carcinoma (ILC): Preliminary results in early-stage patients (pts) stratified according to a validated clinico-pathological model.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.542
Abstract: 542Background: The aim of this analysis was to investigate the distribution of molecular abnormalities and their potential role as therapeutic targets (with particular regard to CDK4/6 alterations) in resected ILC pts, grouped according to prognosis.… read more here.
Keywords: model; generation targeted; early stage; next generation ... See more keywords