Biological Functions of Autophagy Genes: A Disease Perspective
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DOI: 10.1016/j.cell.2018.09.048
Abstract: The lysosomal degradation pathway of autophagy plays a fundamental role in cellular, tissue, and organismal homeostasis and is mediated by evolutionarily conserved autophagy-related (ATG) genes. Definitive etiological links exist between mutations in genes that control… read more here.
Keywords: genes disease; autophagy genes; biological functions; functions autophagy ... See more keywords
The Function of KDEL Receptors as UPR Genes in Disease
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22115436
Abstract: The KDEL receptor retrieval pathway is essential for maintaining resident proteins in the endoplasmic reticulum (ER) lumen. ER resident proteins serve a variety of functions, including protein folding and maturation. Perturbations to the lumenal ER… read more here.
Keywords: genes disease; resident proteins; function kdel; kdel receptors ... See more keywords