Candidate modifier genes for immune function in 22q11.2 deletion syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1057
Abstract: The 22q11.2 deletion syndrome (22q11.2DS) is the most common contiguous microdeletion affecting humans and exhibits extreme phenotypic heterogeneity. Patients can manifest any combination of comorbidities including congenital heart disease, hypoparathyroidism, cleft palate, kidney abnormalities, neurodevelopmental… read more here.
Keywords: deletion syndrome; candidate modifier; genes immune; modifier genes ... See more keywords
Enhanced antitumor efficacy of glutathione-responsive chitosan based nanoparticles through co-delivery of chemotherapeutics, genes, and immune agents.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118384
Abstract: To achieve the co-delivery of chemotherapeutic drugs, genes, and immune agents in a single nanoparticulate system, p-mercaptobenzoic acid-grafted N, N, N-trimethyl chitosan nanoparticles (MT NPs) were successfully synthesized. Paclitaxel (PTX) was encapsulated into the hydrophobic… read more here.
Keywords: immune agents; delivery; enhanced antitumor; chitosan based ... See more keywords
Identification of Key Genes and Immune Infiltrate in Nonalcoholic Steatohepatitis: A Bioinformatic Analysis
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/7561645
Abstract: Background Nonalcoholic steatohepatitis (NASH) can progress to cirrhosis and hepatic carcinoma and is closely associated with changes in the neurological environment. The discovery of new biomarkers would aid in the treatment of NASH. Methods Data… read more here.
Keywords: nonalcoholic steatohepatitis; analysis; genes immune; key genes ... See more keywords
CMTM3 as a Potential New Immune Checkpoint Regulator
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2103515
Abstract: Objectives To evaluate the role of CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) in tumor microenvironment and cancer immunotherapy and explore its potential mechanism. Method The cancer genome map was obtained from the UCSC Xena… read more here.
Keywords: cmtm3 potential; cmtm3; genes immune; cmtm3 expression ... See more keywords
Identification and Analysis of Hub Genes and Immune Cells Associated with the Formation of Acute Aortic Dissection
Sign Up to like & getrecommendations! Published in 2023 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2023/8072369
Abstract: Background Acute type A aortic dissection (AAD) is a catastrophic disease with high mortality, but the pathogenesis has not been fully elucidated. This study is aimed at identifying hub genes and immune cells associated with… read more here.
Keywords: hub genes; dna damage; genes immune; analysis ... See more keywords
Characterization of Immune-Related Genes and Immune Infiltration Features in Epilepsy by Multi-Transcriptome Data
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s360743
Abstract: Background Epilepsy encompasses a group of heterogeneous brain diseases that afflict about 1% of the world’s population. Accumulating evidence shows that the immune system plays a key role in epileptogenesis. Nevertheless, the immune-related mechanisms remain… read more here.
Keywords: infiltration; immune related; genes immune; epilepsy ... See more keywords
Immune Characteristics in Biliary Atresia Based on Immune Genes and Immune Cell Infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.902571
Abstract: Background Biliary atresia (BA) is a serious biliary disease in infancy. Jaundice is the most visual and prominent symptom, and it mainly involves bile duct cells leading to the loss of intrahepatic and extrahepatic bile… read more here.
Keywords: infiltration; cell; immune genes; biliary atresia ... See more keywords
Predictive Analyses of Prognostic-Related Immune Genes and Immune Infiltrates for Glioblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostics"
DOI: 10.3390/diagnostics10030177
Abstract: Glioblastoma (GBM), the most common and aggressive brain tumor, has a very poor outcome and high tumor recurrence rate. The immune system has positive interactions with the central nervous system. Despite many studies investigating immune… read more here.
Keywords: immune infiltrates; immune related; genes immune; related genes ... See more keywords