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   Articles with "genes mirnas" as a keyword



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Differential regulation analysis reveals dysfunctional regulatory mechanism involving transcription factors and microRNAs in gastric carcinogenesis

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recommendations! Published in 2017 at "Artificial intelligence in medicine"

DOI: 10.1016/j.artmed.2017.02.006

Abstract: Gastric cancer (GC) is one of the most incident malignancies in the world. Although lots of featured genes and microRNAs (miRNAs) have been identified to be associated with gastric carcinogenesis, underlying regulatory mechanisms still remain… read more here.

Keywords: analysis; differential regulation; gastric carcinogenesis; genes mirnas ... See more keywords

Analysis of microRNA and Gene Expression Profiles in Alzheimer’s Disease: A Meta-Analysis Approach

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-20959-0

Abstract: Understanding the molecular mechanisms underlying Alzheimer’s disease (AD) is necessary for the diagnosis and treatment of this neurodegenerative disorder. It is therefore important to detect the most important genes and miRNAs, which are associated with… read more here.

Keywords: alzheimer disease; analysis; expression; genes mirnas ... See more keywords
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Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs

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recommendations! Published in 2022 at "Drug Metabolism Reviews"

DOI: 10.1080/03602532.2022.2048846

Abstract: Abstract The human UGT gene superfamily is divided into four subfamilies (UGT1, UGT2, UGT3 and UGT8) that encodes 22 functional enzymes. UGTs are critical for the metabolism and clearance of numerous endogenous and exogenous compounds,… read more here.

Keywords: mirna target; ugt genes; regulation; target sites ... See more keywords

Differentially expressed genes and miRNAs in female osteoporosis patients.

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recommendations! Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000029856

Abstract: Osteoporosis is characterized by lowing bone mineral density. This study aimed to investigate the genes, miRNAs, pathways, and miRNA-gene interaction pairs involved in the pathogenesis of female osteoporosis. The differentially expressed genes (DEGs, GSE62402), differentially… read more here.

Keywords: osteoporosis; differentially expressed; hsa; hsa mir ... See more keywords
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Identification of Key Genes and miRNAs in Osteosarcoma Patients with Chemoresistance by Bioinformatics Analysis

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recommendations! Published in 2018 at "BioMed Research International"

DOI: 10.1155/2018/4761064

Abstract: Chemoresistance is a significant factor associated with poor outcomes of osteosarcoma patients. The present study aims to identify Chemoresistance-regulated gene signatures and microRNAs (miRNAs) in Gene Expression Omnibus (GEO) database. The results of Gene Ontology… read more here.

Keywords: chemoresistance; identification key; analysis; genes mirnas ... See more keywords
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Integrated Analysis of Hub Genes and miRNAs in Dilated Cardiomyopathy

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recommendations! Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/8925420

Abstract: Purpose The aim of this study is to identify hub genes and miRNAs by the miRNA-mRNA interaction network in dilated cardiomyopathy (DCM) disease. Methods The differentially expressed miRNAs (DEMis) and mRNAs (DEMs) were selected using… read more here.

Keywords: network; hub; mir; hub genes ... See more keywords
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Identification of Key Genes and miRNAs Affecting Osteosarcoma Based on Bioinformatics

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recommendations! Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/1015593

Abstract: Methods GSE70367 and GSE69470 were obtained from the GEO database. The differentially expressed genes (DEGs) and miRNAs were analyzed using the GEO2R tool and then visualized with R software. Moreover, the targets of the miRNAs… read more here.

Keywords: identification key; mir 301a; key genes; mir ... See more keywords
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Preeclampsia, Natural History, Genes, and miRNAs Associated with the Syndrome

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recommendations! Published in 2022 at "Journal of Pregnancy"

DOI: 10.1155/2022/3851225

Abstract: Preeclampsia (PE) is a hypertensive disease that affects pregnant women after 20 weeks of gestation. This disease is associated with an important risk of maternal and fetal mortality. PE is described as a placental pathology… read more here.

Keywords: natural history; preeclampsia natural; mirnas associated; pathology ... See more keywords

Integrated Analysis of Crucial Genes and miRNAs Associated with Osteoporotic Fracture of Type 2 Diabetes

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recommendations! Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/3921570

Abstract: Purpose The aim of this study is to explore pathological mechanisms of bone fragility in type 2 diabetes mellitus (T2DM) patients. Methods Identifying common genes for T2DM and osteoporosis by taking the intersection is shared… read more here.

Keywords: signaling pathway; genes mirnas; analysis; type diabetes ... See more keywords
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Exploration of the hub genes and miRNAs in lung adenocarcinoma

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recommendations! Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2019.10478

Abstract: In order to investigate the oncogenic mechanisms of lung adenocarcinoma (LUAD), hub genes can be identified by constructing co-expression networks, and the potential linkages between hub genes, transcription factors (TFs) and microRNAs (miRNAs/miRs) can be… read more here.

Keywords: lung adenocarcinoma; exploration hub; hub; hub genes ... See more keywords