Genes‐to‐Pathways Species Conservation Analysis: Enabling the Exploration of Conservation of Biological Pathways and Processes Across Species
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5600
Abstract: The last two decades have witnessed a strong momentum toward integration of cell‐based and computational approaches in safety assessments. This is fueling a global regulatory paradigm shift toward reduction and replacement of the use of… read more here.
Keywords: toxicology; across species; conservation; chemistry ... See more keywords
Screening of key candidate genes and pathways for osteocytes involved in the differential response to different types of mechanical stimulation using a bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-018-0963-7
Abstract: This study aimed to predict the key genes and pathways that are activated when different types of mechanical loading are applied to osteocytes. mRNA expression datasets (series number of GSE62128 and GSE42874) were obtained from… read more here.
Keywords: types mechanical; genes pathways; different types; response ... See more keywords
Time-series transcriptomic analysis reveals potential genes and pathways involved in the process of monospore formation in Phycocalida chauhanii
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-021-02418-y
Abstract: Nori is the cultivated seaweed with the highest market value in the world. Monospores from the thalli reseed the cultivating nets and provide useful secondary seedlings in nori farming, but the underlying molecular basis remains… read more here.
Keywords: phycocalida chauhanii; genes pathways; time; transcriptomic analysis ... See more keywords
Integrated transcriptomic analysis of Trichosporon Asahii uncovers the core genes and pathways of fluconazole resistance
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18072-9
Abstract: Trichosporon asahii (T. asahii) has emerged as a dangerous pathogen that causes rare but life-threatening infections. Its resistance to certain antifungal agents makes it difficult to treat, especially for patients undergoing long-term antibiotic therapy. In… read more here.
Keywords: genes pathways; trichosporon asahii; asahii; resistance ... See more keywords
Epigenetically dysregulated genes and pathways implicated in the pathogenesis of non-syndromic high myopia
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40299-x
Abstract: Myopia, commonly referred to as nearsightedness, is one of the most common causes of visual disability throughout the world. It affects more people worldwide than any other chronic visual impairment condition. Although the prevalence varies… read more here.
Keywords: pathways implicated; genes pathways; high myopia; myopia ... See more keywords
A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-67699-8
Abstract: Genome–wide association studies (GWAS) have revealed a plethora of putative susceptibility genes for Alzheimer’s disease (AD), with the sole exception of APOE gene unequivocally validated in independent study. Considering that the etiology of complex diseases… read more here.
Keywords: genes pathways; alzheimer disease; analysis strategy; gwas analysis ... See more keywords
Investigation of COVID-19 comorbidities reveals genes and pathways coincident with the SARS-CoV-2 viral disease
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-77632-8
Abstract: The emergence of the SARS-CoV-2 virus and subsequent COVID-19 pandemic initiated intense research into the mechanisms of action for this virus. It was quickly noted that COVID-19 presents more seriously in conjunction with other human… read more here.
Keywords: covid comorbidities; genes pathways; analysis; disease ... See more keywords
Integrative Analysis of Enrichment and Prognostic Value of Ferroptosis-related Genes and Pathways in Multiple Myeloma.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac080
Abstract: Ferroptosis is a non-apoptotic form of cell death caused by excessive iron exposure. The role played by the ferroptosis-related genes and pathways in multiple myeloma (MM) is poorly understood. Here, we show that the ferroptosis-related… read more here.
Keywords: genes pathways; ferroptosis related; pathways multiple; related genes ... See more keywords
Gramene 2021: harnessing the power of comparative genomics and pathways for plant research
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkaa979
Abstract: Gramene (http://www.gramene.org), a knowledgebase founded on comparative functional analyses of genomic and pathway data for model plants and major crops, supports agricultural researchers worldwide. The resource is committed to open access and reproducible science based… read more here.
Keywords: research; plant; genes pathways; pathways plant ... See more keywords
Bioinformatics analysis of key genes and pathways for hepatocellular carcinoma transformed from cirrhosis
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000006938
Abstract: Objective: We aimed to identify some pivotal genes and pathways for hepatocellular carcinoma (HCC) transformation from cirrhosis and explore potential targets for treatment of the disease. Methods: The GSE17548 microarray data were downloaded from Gene… read more here.
Keywords: transformed cirrhosis; hepatocellular carcinoma; pathways hepatocellular; genes pathways ... See more keywords
The Seizure‐Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17352
Abstract: Decades of genetic studies on people with many different epilepsies, and on many nonhuman species, using many different technologies, have generated a huge body of literature about the genes associated with seizures/epilepsy. Collating these data… read more here.
Keywords: pathways treatments; seizure associated; database; genes pathways ... See more keywords