Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments
Sign Up to like & getrecommendations! Published in 2018 at "Nature Genetics"
DOI: 10.1038/s41588-018-0298-2
Abstract: Accumulation of trimethylation of histone H3 at lysine 4 (H3K4me3) on immune-related gene promoters underlies robust transcription during trained immunity. However, the molecular basis for this remains unknown. Here we show three-dimensional chromatin topology enables… read more here.
Keywords: transcription; long noncoding; genes primed; noncoding rnas ... See more keywords