How germline genes promote malignancy in cancer cells
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DOI: 10.1002/bies.202200112
Abstract: Cancers often express hundreds of genes otherwise specific to germ cells, the germline/cancer (GC) genes. Here, we present and discuss the hypothesis that activation of a “germline program” promotes cancer cell malignancy. We do so… read more here.
Keywords: cancer; malignancy; genes promote; germline genes ... See more keywords
Streptococcus pyogenes genes that promote pharyngitis in primates.
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DOI: 10.1172/jci.insight.137686
Abstract: Streptococcus pyogenes (group A streptococcus; GAS) causes 600 million cases of pharyngitis annually worldwide. There is no licensed human GAS vaccine despite a century of research. Although the human oropharynx is the primary site of… read more here.
Keywords: streptococcus pyogenes; genes promote; promote pharyngitis; pharyngitis ... See more keywords