Genetic alteration of colorectal adenoma‐carcinoma sequence among gastric adenocarcinoma and dysplastic lesions in a patient with attenuated familial adenomatous polyposis
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DOI: 10.1002/mgg3.1348
Abstract: Familial adenomatous polyposis (FAP) is characterized by colorectal polyposis and adenocarcinoma that is frequently accompanied by extracolonic neoplasm. The risk of gastric carcinoma is increasing in Western FAP patients as well as Asian patients. read more here.
Keywords: carcinoma; familial adenomatous; genetic alteration; adenocarcinoma ... See more keywords
The genetic alteration spectrum of the SWI/SNF complex: The oncogenic roles of BRD9 and ACTL6A
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DOI: 10.1371/journal.pone.0222305
Abstract: SWItch/Sucrose NonFermentable (SWI/SNF) is a set of multi-subunits chromatin remodeling complexes, playing important roles in a variety of biological processes. Loss-of-function mutations in the genes encoding SWI/SNF subunits have been reported in more than 20%… read more here.
Keywords: oncogenic roles; spectrum swi; genetic alteration; alteration spectrum ... See more keywords
Predictive value of tumor genetic alteration profiling for chemotherapy and EGFR-TKI treatment in advanced NSCLC
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DOI: 10.3892/ol.2020.11502
Abstract: Previous studies have suggested that a variety of tumor driver genetic alterations affected the treatment efficacy of chemotherapy and epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in advanced non-small cell lung cancer (NSCLC). The… read more here.
Keywords: chemotherapy egfr; treatment; genetic alteration; egfr tki ... See more keywords