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   Articles with "genetic ancestry" as a keyword



African Genetic Ancestry, Structural and Social Determinants of Health, and Mortality in Black Adults

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recommendations! Published in 2025 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2025.10016

Abstract: This cohort study investigates the independent associations of African genetic ancestry and structural and social determinants of health with mortality among Black US adults. read more here.

Keywords: genetic ancestry; structural social; determinants health; ancestry structural ... See more keywords

Comparing self-reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models.

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recommendations! Published in 2025 at "Molecular oncology"

DOI: 10.1002/1878-0261.70013

Abstract: While the incidence of endometrial cancer is increasing among all US women, Black women face higher mortality rates. The reasons for this remain unclear. In this study, whole genome differential methylation analysis, along with state‐of‐the‐art… read more here.

Keywords: african ancestry; genetic ancestry; learning models; machine learning ... See more keywords
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How White nationalists mobilize genetics: From genetic ancestry and human biodiversity to counterscience and metapolitics.

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recommendations! Published in 2020 at "American journal of physical anthropology"

DOI: 10.1002/ajpa.24150

Abstract: OBJECTIVES Our aim in this study was to understand how genetics ideas are appropriated and mobilized online toward the political projects of White nationalism and the alt right. Studying three different online venues, we investigated… read more here.

Keywords: genetics; genetic ancestry; human biodiversity; metapolitics ... See more keywords

Abandoning the word Caucasian.

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recommendations! Published in 2023 at "Journal of genetic counseling"

DOI: 10.1002/jgc4.1730

Abstract: Traditionally, the field of genetics has used patient-reported genetic ancestry to assist in risk assessment, calculate detection rates, and understand residual risks for recessive or X-linked genetic diseases. Patient-reported genetic ancestry is useful for variant… read more here.

Keywords: ancestry; genetic ancestry; word caucasian; abandoning word ... See more keywords

Influence of Genetic Ancestry on Human Serum Proteome.

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recommendations! Published in 2020 at "American journal of human genetics"

DOI: 10.1016/j.ajhg.2020.01.016

Abstract: Disease risk varies significantly between ethnic groups, however, the clinical significance and implications of these observations are poorly understood. Investigating ethnic differences within the human proteome may shed light on the impact of ancestry on… read more here.

Keywords: biomarker; ancestry human; human serum; genetic ancestry ... See more keywords
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Cigarette smoking behaviors and the importance of ethnicity and genetic ancestry

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recommendations! Published in 2021 at "Translational Psychiatry"

DOI: 10.1038/s41398-021-01244-7

Abstract: Cigarette smoking contributes to numerous diseases and is one of the leading causes of death in the United States. Smoking behaviors vary widely across race/ethnicity, but it is not clear why. Here, we examine the… read more here.

Keywords: ethnicity; cigarette smoking; smoking behaviors; smoking ... See more keywords

Genetic ancestry in precision medicine is reshaping the race debate

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recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2203033119

Abstract: Precision medicine is an emerging field with immense potential for better understanding of diseases and improved treatment outcomes (1). Its focus: patterns of human genetic variation in populations and individuals—and how such patterns influence disease… read more here.

Keywords: race; ancestry precision; genetic ancestry; precision medicine ... See more keywords

Genetic ancestry and risk allele C9orf72 rs3849942 T for amyotrophic lateral sclerosis in Latin American populations

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recommendations! Published in 2024 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"

DOI: 10.1080/21678421.2024.2447459

Abstract: Abstract This study examines the relationship between genetic ancestry and the rs3849942 T allele, linked to ALS, in 347 Latin American individuals from the 1000 Genomes Project. Ancestry proportions were estimated using 446 AIMs, and… read more here.

Keywords: latin american; genetic ancestry; rs3849942; amyotrophic lateral ... See more keywords

European genetic ancestry associated with risk of childhood ependymoma.

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recommendations! Published in 2020 at "Neuro-oncology"

DOI: 10.1093/neuonc/noaa130

Abstract: BACKGROUND Ependymoma is a histologically defined central nervous system tumor most commonly occurring in childhood. Population-level incidence differences by race/ethnicity are observed, with individuals of European ancestry at highest risk. We aimed to determine whether… read more here.

Keywords: risk; genetic ancestry; ependymoma; european genetic ... See more keywords

Genetic ancestry superpopulations show distinct prevalence and outcomes across pediatric central nervous system tumors from the Pediatric Brain Tumor Atlas and Pediatric Neuro-Oncology Consortium

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf017

Abstract: Background: Central nervous system (CNS) tumors lead to cancer-related mortality in children. Genetic ancestry-associated cancer prevalence and outcomes have been studied, but is limited. Methods: We performed genetic ancestry prediction in 1,484 pediatric patients with… read more here.

Keywords: oncology; central nervous; genetic ancestry; nervous system ... See more keywords

Dissecting the Interplay Between Genetic Ancestry and Neighborhood Socioeconomic Status on Triple Negative Breast Cancer.

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recommendations! Published in 2022 at "Annals of surgery"

DOI: 10.1097/sla.0000000000005554

Abstract: OBJECTIVE To investigate the impact of global and local genetic ancestry and neighborhood socioeconomic status (nSES), on breast cancer (BC) subtype, and gene expression. SUMMARY OF BACKGROUND DATA Higher rates of aggressive BC subtypes (TNBC)… read more here.

Keywords: neighborhood socioeconomic; ancestry; genetic ancestry; breast cancer ... See more keywords