Modeling Retinal Diseases Using Genetic Approaches in Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7720-8_3
Abstract: Genetic mouse models mimicking human diseases have been developed and utilized for retinal research in various topics, involving anatomy, physiology, biochemistry, and pathology. The main reasons why mouse models are important for retinal research include… read more here.
Keywords: mouse models; diseases using; using genetic; modeling retinal ... See more keywords
Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches.
Sign Up to like & getrecommendations! Published in 2019 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.9b01073
Abstract: Understanding the cellular uptake mechanism of materials is of fundamental importance that would be beneficial for materials design with enhanced biological functions. Herein, we report the interplay of pharmacological and genetic approaches to minimize the… read more here.
Keywords: interplay pharmacological; amphiphilic polymers; polymer; genetic approaches ... See more keywords
Novel genetic approaches to behavior in Drosophila
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurogenetics"
DOI: 10.1080/01677063.2017.1395875
Abstract: Abstract The study of behavior requires manipulation of the controlling neural circuits. The fruit fly, Drosophila melanogaster, is an ideal model for studying behavior because of its relatively small brain and the numerous sophisticated genetic… read more here.
Keywords: genetic approaches; approaches behavior; novel genetic; behavior drosophila ... See more keywords
Exploring the roles of prostanoids, leukotriens, and dietary fatty acids in cutaneous inflammatory diseases: Insights from pharmacological and genetic approaches.
Sign Up to like & getrecommendations! Published in 2023 at "Immunological reviews"
DOI: 10.1111/imr.13193
Abstract: Prostanoids and leukotrienes (LTs) are representative of ω6 fatty acid-derived metabolites that exert their actions through specific receptors on the cell surface. These lipid mediators, being unstable in vivo, act locally at their production sites;… read more here.
Keywords: genetic approaches; fatty acid; lipid mediators; cutaneous inflammatory ... See more keywords
Genetic approaches to dissect plant nonhost resistance mechanisms
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Plant Pathology"
DOI: 10.1111/mpp.13290
Abstract: Abstract Nonhost resistance (NHR) refers to the immunity of most tested genotypes of a plant species to most tested variants of a pathogen species. Thus, NHR is broad spectrum and durable in nature and constitutes… read more here.
Keywords: nonhost resistance; genetic approaches; dissect plant; resistance ... See more keywords
Genetic Approaches to Bronchopulmonary Dysplasia.
Sign Up to like & getrecommendations! Published in 2019 at "NeoReviews"
DOI: 10.1542/neo.20-5-e272
Abstract: Bronchopulmonary dysplasia (BPD) remains a common and challenging complication of prematurity, with limited effective strategies at the neonatologist's disposal. Throughout the years, our understanding of this complex syndrome has broadened. Instead of solely attributing this… read more here.
Keywords: genetic approaches; dysplasia; approaches bronchopulmonary; bronchopulmonary dysplasia ... See more keywords
Forward Genetics in Apicomplexa Biology: The Host Side of the Story
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.878475
Abstract: Forward genetic approaches have been widely used in parasitology and have proven their power to reveal the complexities of host-parasite interactions in an unbiased fashion. Many aspects of the parasite’s biology, including the identification of… read more here.
Keywords: forward genetics; genetic approaches; forward genetic; host ... See more keywords
Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00288
Abstract: Osteoporosis is a complex condition with contributions from, and interactions between, multiple genetic loci and environmental factors. This review summarizes key advances in the application of genetic approaches for the identification of osteoporosis susceptibility genes.… read more here.
Keywords: susceptibility; analysis; identification; discovery ... See more keywords
Genetic approaches to elucidating cortical and hippocampal GABAergic interneuron diversity
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2024.1414955
Abstract: GABAergic interneurons (INs) in the mammalian forebrain represent a diverse population of cells that provide specialized forms of local inhibition to regulate neural circuit activity. Over the last few decades, the development of a palette… read more here.
Keywords: elucidating cortical; hippocampal gabaergic; cortical hippocampal; genetic approaches ... See more keywords
Genetic approaches to exploit landraces for improvement of Triticum turgidum ssp. durum in the age of climate change
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1101271
Abstract: Addressing the challenges of climate change and durum wheat production is becoming an important driver for food and nutrition security in the Mediterranean area, where are located the major producing countries (Italy, Spain, France, Greece,… read more here.
Keywords: approaches exploit; climate change; genetic approaches; durum ... See more keywords
Statistical Genetic Approaches to Investigate Genotype-by-Environment Interaction: Review and Novel Extension of Models
Sign Up to like & getrecommendations! Published in 2024 at "Genes"
DOI: 10.3390/genes15050547
Abstract: Statistical genetic models of genotype-by-environment (G×E) interaction can be divided into two general classes, one on G×E interaction in response to dichotomous environments (e.g., sex, disease-affection status, or presence/absence of an exposure) and the other… read more here.
Keywords: genotype environment; environment interaction; environment; genetic approaches ... See more keywords