Articles with "genetic associations" as a keyword



Sex Differences in Genetic Associations With Longevity

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Published in 2018 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2018.1670

Abstract: Key Points Question Are there sex differences in genetic associations with longevity? Findings In this case-control study of 2178 cases and 2299 controls who were Chinese with Han ethnicity, sex-specific genome-wide association study and sex-specific… read more here.

Keywords: genetic associations; longevity; sex differences; differences genetic ... See more keywords

Mapping Genetic Associations With Functional Brain Area Alterations in Schizophrenia and Implications for Cortical Development

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Published in 2025 at "Brain and Behavior"

DOI: 10.1002/brb3.70688

Abstract: While prior studies have identified regional reduction in gray matter (GM) volume in schizophrenia, it remains unclear whether these alterations are concentrated in specific brain functional areas and how they relate to genetic factors. This… read more here.

Keywords: associations functional; brain; genetic associations; cortical development ... See more keywords
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17 FUMA: FUNCTIONAL MAPPING AND ANNOTATION OF GENETIC ASSOCIATIONS

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Published in 2019 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2017.08.018

Abstract: Background A main challenge in genome-wide association studies (GWAS) is to prioritize genetic variants and identify potential causal mechanisms of human diseases. Although a variety of bioinformatics tools are now available for downstream analyses of… read more here.

Keywords: genetic associations; mapping; snps; genetic variants ... See more keywords

Genetic Associations Between Executive Functions and a General Factor of Psychopathology.

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Published in 2019 at "Journal of the American Academy of Child and Adolescent Psychiatry"

DOI: 10.1016/j.jaac.2019.05.006

Abstract: OBJECTIVE Symptoms of psychopathology covary across diagnostic boundaries, and a family history of elevated symptoms for a single psychiatric disorder places an individual at heightened risk for a broad range of other psychiatric disorders. Both… read more here.

Keywords: genetic associations; risk; executive functions; cognitive abilities ... See more keywords

Genetic associations between growth traits and age at first calving in Guzera cattle using random regression models

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Published in 2021 at "Livestock Science"

DOI: 10.1016/j.livsci.2021.104585

Abstract: Abstract The aim of this study was to estimate genetic associations between body weight (BW), scrotal circumference (SC), and age at first calving (AFC) in Guzera cattle using random regression models. The analyses used 159,366… read more here.

Keywords: genetic associations; age; age first; guzera cattle ... See more keywords

Magical thinking as a bio-psychological developmental disposition for cognitive and affective symptoms intensity in schizotypy: Traits and genetic associations

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Published in 2020 at "Personality and Individual Differences"

DOI: 10.1016/j.paid.2020.110498

Abstract: Abstract Schizotypy refers to a set of heritable, continuously distributed personality traits that resemble signs and symptoms of schizophrenia in the general population. It has been argued that studying the genetic background of schizotypy may… read more here.

Keywords: magical thinking; schizotypal traits; schizotypy; genetic associations ... See more keywords

iPSC-modelling reveals genetic associations and morphological alterations of oligodendrocytes in schizophrenia

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Published in 2025 at "Translational Psychiatry"

DOI: 10.1038/s41398-025-03509-x

Abstract: There is strong evidence for a genetically driven neuronal contribution in schizophrenia (SCZ). Although imaging and postmortem studies also provide evidence for white matter alterations with implications of the oligodendroglial lineage in SCZ, it is… read more here.

Keywords: genetics; white matter; genetic associations; oligodendroglial lineage ... See more keywords
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Genetic associations of protein-coding variants in human disease

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Published in 2022 at "Nature"

DOI: 10.1038/s41586-022-04394-w

Abstract: Genome-wide association studies (GWAS) have identified thousands of genetic variants linked to the risk of human disease. However, GWAS have so far remained largely underpowered in relation to identifying associations in the rare and low-frequency… read more here.

Keywords: genetic associations; associations protein; disease; coding variants ... See more keywords

Genetic associations with educational fields.

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Published in 2025 at "Nature genetics"

DOI: 10.1038/s41588-025-02391-z

Abstract: Educational field choices shape careers, wellbeing and the societal skill distribution, yet genetic influences on what people study remain poorly understood. Here we show that genetic factors are associated with educational field specializations using genome-wide… read more here.

Keywords: field; associations educational; genetic associations; genome wide ... See more keywords

Social and genetic associations with educational performance in a Scandinavian welfare state

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2201869119

Abstract: Significance Children of highly educated parents perform better in school; this may be due to social environments or genes. Most studies do not distinguish between the two, meaning that genetic associations may confound environmental explanations… read more here.

Keywords: social genetic; welfare; genetic associations; welfare state ... See more keywords

Uncovering genetic associations in the human diseasome using an endophenotype-augmented disease network

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Published in 2024 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btae126

Abstract: Abstract Motivation Many diseases, particularly cardiometabolic disorders, exhibit complex multimorbidities with one another. An intuitive way to model the connections between phenotypes is with a disease-disease network (DDN), where nodes represent diseases and edges represent… read more here.

Keywords: disease; genetic associations; associations human; network ... See more keywords