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Published in 2018 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2018.1670
Abstract: Key Points Question Are there sex differences in genetic associations with longevity? Findings In this case-control study of 2178 cases and 2299 controls who were Chinese with Han ethnicity, sex-specific genome-wide association study and sex-specific…
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Keywords:
genetic associations;
longevity;
sex differences;
differences genetic ... See more keywords
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Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70688
Abstract: While prior studies have identified regional reduction in gray matter (GM) volume in schizophrenia, it remains unclear whether these alterations are concentrated in specific brain functional areas and how they relate to genetic factors. This…
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Keywords:
associations functional;
brain;
genetic associations;
cortical development ... See more keywords
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Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.018
Abstract: Background A main challenge in genome-wide association studies (GWAS) is to prioritize genetic variants and identify potential causal mechanisms of human diseases. Although a variety of bioinformatics tools are now available for downstream analyses of…
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Keywords:
genetic associations;
mapping;
snps;
genetic variants ... See more keywords
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Published in 2019 at "Journal of the American Academy of Child and Adolescent Psychiatry"
DOI: 10.1016/j.jaac.2019.05.006
Abstract: OBJECTIVE Symptoms of psychopathology covary across diagnostic boundaries, and a family history of elevated symptoms for a single psychiatric disorder places an individual at heightened risk for a broad range of other psychiatric disorders. Both…
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Keywords:
genetic associations;
risk;
executive functions;
cognitive abilities ... See more keywords
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Published in 2021 at "Livestock Science"
DOI: 10.1016/j.livsci.2021.104585
Abstract: Abstract The aim of this study was to estimate genetic associations between body weight (BW), scrotal circumference (SC), and age at first calving (AFC) in Guzera cattle using random regression models. The analyses used 159,366…
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Keywords:
genetic associations;
age;
age first;
guzera cattle ... See more keywords
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Published in 2020 at "Personality and Individual Differences"
DOI: 10.1016/j.paid.2020.110498
Abstract: Abstract Schizotypy refers to a set of heritable, continuously distributed personality traits that resemble signs and symptoms of schizophrenia in the general population. It has been argued that studying the genetic background of schizotypy may…
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Keywords:
magical thinking;
schizotypal traits;
schizotypy;
genetic associations ... See more keywords
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Published in 2025 at "Translational Psychiatry"
DOI: 10.1038/s41398-025-03509-x
Abstract: There is strong evidence for a genetically driven neuronal contribution in schizophrenia (SCZ). Although imaging and postmortem studies also provide evidence for white matter alterations with implications of the oligodendroglial lineage in SCZ, it is…
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Keywords:
genetics;
white matter;
genetic associations;
oligodendroglial lineage ... See more keywords
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Published in 2022 at "Nature"
DOI: 10.1038/s41586-022-04394-w
Abstract: Genome-wide association studies (GWAS) have identified thousands of genetic variants linked to the risk of human disease. However, GWAS have so far remained largely underpowered in relation to identifying associations in the rare and low-frequency…
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Keywords:
genetic associations;
associations protein;
disease;
coding variants ... See more keywords
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Published in 2025 at "Nature genetics"
DOI: 10.1038/s41588-025-02391-z
Abstract: Educational field choices shape careers, wellbeing and the societal skill distribution, yet genetic influences on what people study remain poorly understood. Here we show that genetic factors are associated with educational field specializations using genome-wide…
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Keywords:
field;
associations educational;
genetic associations;
genome wide ... See more keywords
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201869119
Abstract: Significance Children of highly educated parents perform better in school; this may be due to social environments or genes. Most studies do not distinguish between the two, meaning that genetic associations may confound environmental explanations…
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Keywords:
social genetic;
welfare;
genetic associations;
welfare state ... See more keywords
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Published in 2024 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btae126
Abstract: Abstract Motivation Many diseases, particularly cardiometabolic disorders, exhibit complex multimorbidities with one another. An intuitive way to model the connections between phenotypes is with a disease-disease network (DDN), where nodes represent diseases and edges represent…
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Keywords:
disease;
genetic associations;
associations human;
network ... See more keywords