Genetic Bases of Complex Traits: From Quantitative Trait Loci to Prediction.
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DOI: 10.1007/978-1-0716-2205-6_1
Abstract: Conceived as a general introduction to the book, this chapter is a reminder of the core concepts of genetic mapping and molecular marker-based prediction. It provides an overview of the principles and the evolution of… read more here.
Keywords: bases complex; genetic bases; marker; prediction ... See more keywords
Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits
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DOI: 10.1017/s0033291718001812
Abstract: Abstract Background Cardiovascular diseases represent a major health issue in patients with schizophrenia (SCZ) and bipolar disorder (BD), but the exact nature of cardiometabolic (CM) abnormalities involved and the underlying mechanisms remain unclear. Psychiatric medications… read more here.
Keywords: exploring shared; genetic bases; bipolar disorder; shared genetic ... See more keywords
Looking into the genetic bases of OCD dimensions: a pilot genome-wide association study
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DOI: 10.1038/s41398-020-0804-z
Abstract: The multidimensional nature of obsessive-compulsive disorder (OCD) has been consistently reported. Clinical and biological characteristics have been associated with OCD dimensions in different ways. Studies suggest the existence of specific genetic bases for the different… read more here.
Keywords: genome wide; genetic bases; looking genetic; bases ocd ... See more keywords
Genetic bases of the nutritional approach to migraine
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DOI: 10.1080/10408398.2018.1450215
Abstract: ABSTRACT Migraine is a common multifactorial and polygenic neurological disabling disorder characterized by a genetic background and associated to environmental, hormonal and food stimulations. A large series of evidence suggest a strong correlation between nutrition… read more here.
Keywords: migraine; genetic bases; approach migraine; bases nutritional ... See more keywords
Genetic bases of pheochromocytoma and paraganglioma.
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DOI: 10.1530/endoabs.81.s9.1
Abstract: The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly complex over the last two decades. The list of genes involved in the development of these tumors has grown steadily, and there are currently more… read more here.
Keywords: pheochromocytoma paraganglioma; genetic bases; endocrinology; ppgl ... See more keywords
Genetic bases of dilated cardiomyopathy.
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DOI: 10.2459/jcm.0000000000000432
Abstract: Cardiomyopathies represent a wide and heterogeneous group of diseases wherein a genetic cause has been consistently identified.Dilated cardiomyopathy (DCM) is characterized by ventricular dilation and progressive systolic dysfunction, and it is the most common form… read more here.
Keywords: dilated cardiomyopathy; medicine; bases dilated; genetic bases ... See more keywords