Genetic Changes of P53 and Kras in Gallbladder Carcinoma in Kumaon Region of Uttarakhand
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-019-00283-0
Abstract: Gallbladder carcinoma is a highly lethal but relatively rare neoplasm of the digestive tract. p53 mutations are one of the most frequent genetic alterations in human cancers and are thought to play a role in… read more here.
Keywords: carcinoma; changes p53; invasion; p53 kras ... See more keywords
Genetic changes associated to tigecycline resistance in Staphylococcus aureus in-vitro selected mutants belonging to different lineages: Genetic changes in S. aureus mutants resistant to tigecycline.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2021.106304
Abstract: Tigecycline resistance remains rare in S. aureus worldwide. Twelve TGC resistant S. aureus mutants (TRSAm) were obtained displaying an increase in their efflux activity. The isolates belonged to 7 different genetic lineages, with predominance of CC5. Diverse genetic changes in… read more here.
Keywords: tigecycline resistance; amino acid; resistance; genetic changes ... See more keywords
Astronaut twins study spots subtle genetic changes caused by space travel.
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/d41586-019-01149-y
Abstract: Some initial effects of long-term spaceflight ebbed in the months after astronaut Scott Kelly returned to Earth. Some initial effects of long-term spaceflight ebbed in the months after astronaut Scott Kelly returned to Earth. read more here.
Keywords: subtle genetic; astronaut twins; spots subtle; twins study ... See more keywords
How many genetic changes create new species?
Sign Up to like & getrecommendations! Published in 2021 at "Science"
DOI: 10.1126/science.abf6671
Abstract: Speciation in plants and animals can involve differentiation across many genetic regions The formation of new species generates biodiversity and is often driven by evolution through natural selection. However, the number of genetic changes involved… read more here.
Keywords: changes create; new species; many genetic; selection ... See more keywords
Molecular genetic changes in solid pseudopapillary neoplasms (SPN) of the pancreas.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.4_suppl.749
Abstract: 749Background: Solid Pseudopapillary Neoplasms (SPNs) of the pancreas are rare accounting for 1-2% of all pancreatic tumors. Previous studies had shown that a pathogenic mutation of the CTNNB1 gene... read more here.
Keywords: neoplasms spn; pseudopapillary neoplasms; solid pseudopapillary; molecular genetic ... See more keywords
Comparative Genome Sequencing Reveals Within-Host Genetic Changes in Neisseria meningitidis during Invasive Disease
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169892
Abstract: Some members of the physiological human microbiome occasionally cause life-threatening disease even in immunocompetent individuals. A prime example of such a commensal pathogen is Neisseria meningitidis, which normally resides in the human nasopharynx but is… read more here.
Keywords: host genetic; within host; disease; host ... See more keywords
Recent advances in blood group genotyping
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Botany"
DOI: 10.21037/aob-21-8
Abstract: Red blood cell (RBC) antigen typing of both recipients and donors is vital for safe and effective transfusion. Despite the existence of >330 RBC antigens, current routine pre-transfusion testing only includes matching the patient and… read more here.
Keywords: rbc antigen; genetic changes; blood; antigen typing ... See more keywords
Genetic Changes Driving Immunosuppressive Microenvironments in Oral Premalignancy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.840923
Abstract: Oral premalignant lesions (OPLs) are the precursors to oral cavity cancers, and have variable rates of progression to invasive disease. As an intermediate state, OPLs have acquired a subset of the genomic alterations while arising… read more here.
Keywords: oral premalignancy; genetic changes; driving immunosuppressive; changes driving ... See more keywords
Somatic, Genetic and Epigenetic Changes in Nephrogenic Rests and Their Role in the Transformation to Wilms Tumors, a Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15051363
Abstract: Simple Summary We reviewed all studies investigating molecular changes in nephrogenic rests (NR), the presumed precursor lesions of Wilms tumors (WT) being the most frequent malignant childhood renal tumors, between 1990 and 2022. Only 23… read more here.
Keywords: review; changes nephrogenic; somatic genetic; nephrogenic rests ... See more keywords