Reassigning stop codons via translation termination: How a few eukaryotes broke the dogma
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201600213
Abstract: The genetic code determines how amino acids are encoded within mRNA. It is universal among the vast majority of organisms, although several exceptions are known. Variant genetic codes are found in ciliates, mitochondria, and numerous… read more here.
Keywords: codons via; genetic codes; stop codons; reassigning stop ... See more keywords
Synthetic genome recoding: new genetic codes for new features
Sign Up to like & getrecommendations! Published in 2017 at "Current Genetics"
DOI: 10.1007/s00294-017-0754-z
Abstract: Full genome recoding, or rewriting codon meaning, through chemical synthesis of entire bacterial chromosomes has become feasible in the past several years. Recoding an organism can impart new properties including non-natural amino acid incorporation, virus… read more here.
Keywords: new genetic; genome recoding; genetic codes; synthetic genome ... See more keywords
Optimal Noise-Immune Genetic Codes
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DOI: 10.1007/s10559-019-00110-1
Abstract: DNA symmetry is used to generate optimal genetic codes whose noise immunity with respect to polarity of amino acids in case of mutations in nucleotides is much greater than immunity of standard codes. Noise immunity… read more here.
Keywords: noise immune; immunity; immune genetic; genetic codes ... See more keywords
An amino acid-swapped genetic code.
Sign Up to like & getrecommendations! Published in 2020 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.0c00196
Abstract: Preventing the escape of hazardous genes from genetically modified organisms (GMOs) into the environment is one of the most important issues in biotechnology research. Various strategies were developed to create "genetic firewalls" that prevent the… read more here.
Keywords: amino acid; acid swapped; genetic codes; swapped genetic ... See more keywords
Refactored genetic codes enable bidirectional genetic isolation
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DOI: 10.1126/science.add8943
Abstract: The near-universal genetic code defines the correspondence between codons in genes and amino acids in proteins. We refactored the structure of the genetic code in Escherichia coli and created orthogonal genetic codes that restrict the… read more here.
Keywords: genetic information; genetic code; genetic codes; code ... See more keywords
Symmetrical Properties of Graph Representations of Genetic Codes: From Genotype to Phenotype
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DOI: 10.3390/sym10090388
Abstract: It has long been claimed that the mitochondrial genetic code possesses more symmetries than the Standard Genetic Code (SGC). To test this claim, the symmetrical structure of the SGC is compared with noncanonical genetic codes.… read more here.
Keywords: symmetrical properties; genetic codes; graph representations; representations genetic ... See more keywords