GWAS summary-based pathway analysis correcting for the genetic confounding impact of environmental exposures
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbx025
Abstract: Genome-wide association study (GWAS)-based pathway association analysis is a powerful approach for the genetic studies of human complex diseases. However, the genetic confounding effects of environment exposure-related genes can decrease the accuracy of GWAS-based pathway… read more here.
Keywords: analysis; environmental exposures; genetic confounding; gwas summary ... See more keywords
Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Epidemiology"
DOI: 10.1093/ije/dyz095
Abstract: Abstract Background Maternal pre-pregnancy body mass index (BMI) is positively associated with offspring birth weight (BW) and BMI in childhood and adulthood. Each of these associations could be due to causal intrauterine effects, or confounding… read more here.
Keywords: index; bmi; birth; genetic confounding ... See more keywords