The impact on estimations of genetic correlations by the use of super‐normal, unscreened, and family‐history screened controls in genome wide case–control studies
Sign Up to like & getrecommendations! Published in 2020 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22281
Abstract: Traditionally, in normal case–control studies of disorder A, the controls are defined as those not developing the disorder. However, in genome wide association (GWA) studies, controls are sometimes (a) unscreened or (b) screened for both… read more here.
Keywords: genome wide; control studies; genetic correlations; normal controls ... See more keywords
Patterns of Psychiatric Comorbidity and Genetic Correlations Provide New Insights Into Differences Between Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2019 at "Biological psychiatry"
DOI: 10.1016/j.biopsych.2019.04.021
Abstract: BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) share common genetic factors but seem to have specific patterns of psychiatric comorbidities. There are few systematic studies on adults; therefore, we compared psychiatric comorbidities in… read more here.
Keywords: disorder; deficit hyperactivity; adhd asd; attention deficit ... See more keywords
SU101 IDENTIFICATION OF KEY SNPS AND PATHWAYS UNDERLYING DIFFERENTIAL GENETIC CORRELATIONS BETWEEN EDUCATION AND COGNITION ON SCHIZOPHRENIA
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.290
Abstract: Background Prior investigation of the genetic architecture of educational attainment and schizophrenia has reported a counter-intuitive positive genetic correlation between these phenotypes. Yet, it has been widely reported that debilitating cognitive impairments are a primary… read more here.
Keywords: schizophrenia; snps; genetic correlations; correlation ... See more keywords
Meta-analysis of genetic parameters for economic traits in buffaloes
Sign Up to like & getrecommendations! Published in 2021 at "Livestock Science"
DOI: 10.1016/j.livsci.2021.104614
Abstract: Abstract Reliable estimates of genetic parameters for economic traits in buffaloes can be achieved through a meta-analysis that brings together several studies and accounts for the variation among them. This study aimed to perform a… read more here.
Keywords: meta analysis; parameters economic; milk; genetic parameters ... See more keywords
Exploring the genetic heterogeneity in major depression across diagnostic criteria
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DOI: 10.1038/s41380-021-01231-w
Abstract: Major depressive disorder (MDD) is defined differently across genetic research studies and this may be a key source of heterogeneity. While previous literature highlights differences between minimal and strict phenotypes, the components contributing to this… read more here.
Keywords: depression; heterogeneity; major depression; depression phenotypes ... See more keywords
Genetic overlap between psychotic experiences in the community across age and with psychiatric disorders
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-0765-2
Abstract: This study explores the degree to which genetic influences on psychotic experiences are stable across adolescence and adulthood, and their overlap with psychiatric disorders. Genome-wide association results were obtained for adolescent psychotic experiences and negative… read more here.
Keywords: across age; psychotic experiences; psychiatric disorders; auditory visual ... See more keywords
Heritability and genetic correlations of plasma metabolites of pigs with production, resilience and carcass traits under natural polymicrobial disease challenge
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99778-9
Abstract: Metabolites in plasma of healthy nursery pigs were quantified using nuclear magnetic resonance. Heritabilities of metabolite concentration were estimated along with their phenotypic and genetic correlations with performance, resilience, and carcass traits in growing pigs… read more here.
Keywords: challenge; disease; resilience; genetic correlations ... See more keywords
279GWAS of heart rate in 87,759 Chinese subjects highlighted its genetic correlations with cardiometabolic traits
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Epidemiology"
DOI: 10.1093/ije/dyab168.733
Abstract: Resting heart rate (RHR) has been associated with risks of mortality and multiple chronic diseases. Previous studies, predominantly conducted in Europeans, have reported 91 independent variants associated with RHR and its genetic correlations with several… read more here.
Keywords: rhr; correlations cardiometabolic; cardiometabolic traits; genetic correlations ... See more keywords
Genetic and phenotypic relationships between ewe reproductive performance and wool and growth traits in Uruguayan Ultrafine Merino sheep
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Animal Science"
DOI: 10.1093/jas/skad071
Abstract: Abstract This study reports genetic parameters for yearling and adult wool and growth traits, and ewe reproductive performance. Data were sourced from an Uruguayan Merino flock involved in a long-term selection program focused on reduced… read more here.
Keywords: reproduction traits; ewe reproductive; genetic correlations; performance ... See more keywords
Genetic parameters of methane emissions determined using portable accumulation chambers in lambs and ewes grazing pasture and genetic correlations with emissions determined in respiration chambers1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Animal Science"
DOI: 10.1093/jas/sky187
Abstract: Abstract Methane (CH4) emission traits were previously found to be heritable and repeatable in sheep fed alfalfa pellets in respiration chambers (RC). More rapid screening methods are, however, required to increase genetic progress and to… read more here.
Keywords: lambs ewes; ch4 co2; measured using; ch4 ... See more keywords
Non-consumptive effects of predation: does perceived risk strengthen the genetic integration of behaviour and morphology in stickleback?
Sign Up to like & getrecommendations! Published in 2019 at "Ecology letters"
DOI: 10.1111/ele.13413
Abstract: Predators can shape genetic correlations in prey by altering prey perception of risk. We manipulated perceived risk to test whether such non-consumptive effects tightened behavioural trait correlations in wild-caught stickleback from high- compared to low-risk… read more here.
Keywords: risk; morphology; consumptive effects; genetic correlations ... See more keywords