Articles with "genetic dependency" as a keyword



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Abstract 3452: The cohesin subunitSTAG1is a hardwired genetic dependency ofSTAG2mutant cancer cells

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-3452

Abstract: Recent genome analyses have identified recurrent mutations in subunits of the cohesin complex in human cancer. Cohesin is a chromosomal factor that is essential for sister chromatid cohesion and cell division and that contributes to… read more here.

Keywords: stag2; genetic dependency; cohesin; cancer ... See more keywords