Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Gut"
DOI: 10.1136/gutjnl-2017-315920
Abstract: Objective Serrated colorectal cancer (CRC) accounts for approximately 25% of cases and includes tumours that are among the most treatment resistant and with worst outcomes. This CRC subtype is associated with activating mutations in the… read more here.
Keywords: serrated crc; genetic editing; organoids provides; carcinogenesis ... See more keywords
OsmiR535, a Potential Genetic Editing Target for Drought and Salinity Stress Tolerance in Oryza sativa
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DOI: 10.3390/plants9101337
Abstract: OsmiR535 belongs to the miR156/miR529/miR535 superfamily, a highly conserved miRNA family in plants. OsmiR535 is involved in regulating the cold-stress response, modulating plant development, and determining panicle architecture and grain length. However, the role that… read more here.
Keywords: tolerance; drought salinity; genetic editing; stress ... See more keywords