Associations between alcohol use and peripheral, genetic, and epigenetic markers of oxytocin in a general sample of young and older adults
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2425
Abstract: Human and nonhuman animal research suggests that greater oxytocin (OT) activity is protective against harmful substance use. Most research on this topic is preclinical, with few studies evaluating the association between substance use and individual… read more here.
Keywords: associations alcohol; sample; peripheral genetic; alcohol use ... See more keywords
High genetic and epigenetic variation of transposable elements: Potential drivers to rapid adaptive evolution for the noxious invasive weed Mikania micrantha
Sign Up to like & getrecommendations! Published in 2021 at "Ecology and Evolution"
DOI: 10.1002/ece3.8075
Abstract: Abstract Why invasive species can rapidly adapt to novel environments is a puzzling question known as the genetic paradox of invasive species. This paradox is explainable in terms of transposable elements (TEs) activity, which are… read more here.
Keywords: variation; mikania micrantha; epigenetic variation; genetic epigenetic ... See more keywords
Genetic and epigenetic factors influencing vitamin D status
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26216
Abstract: The global prevalence of vitamin D deficiency appears to be increasing, and the impact of this on human health is important because of the association of vitamin D insufficiency with increased risk of osteoporosis, cardiovascular… read more here.
Keywords: vitamin status; genetic epigenetic; factors influencing; vitamin ... See more keywords
Oxidative, inflammatory, genetic, and epigenetic biomarkers associated with chronic obstructive pulmonary disorder
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27181
Abstract: A large body of evidence indicates that chronic obstructive pulmonary disorder (COPD) is accompanied by oxidative stress and inflammatory and genetic pathways. Epidemiological studies indicate that COPD is a major cause of mortality and morbidity… read more here.
Keywords: chronic obstructive; obstructive pulmonary; genetic epigenetic; pulmonary disorder ... See more keywords
Parkinsonism due to A53E α‐synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27506
Abstract: SNCA mutations cause autosomal dominant parkinsonism and inform our understanding of the molecular underpinnings of synucleinopathies. The most recently identified mutation, p.Ala53Glu (A53E), has only been observed in Finland. The objectives of this study were… read more here.
Keywords: clinical genetic; epigenetic biochemical; biochemical features; genetic epigenetic ... See more keywords
Genetic and epigenetic control of the plant metabolome.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202200104
Abstract: Plant metabolites are mainly produced through chemical reactions catalysed by enzymes encoded in the genome. Mutations in enzyme-encoding or transcription factor-encoding genes can alter the metabolome by changing the enzyme's catalytic activity or abundance, respectively.… read more here.
Keywords: metabolism; control; epigenetic control; genetic epigenetic ... See more keywords
Interplay Between Genetic and Epigenetic Changes in Breast Cancer Subtypes.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8751-1_2
Abstract: Breast cancer is the most common cancer among women and represents one of the top five leading causes of cancer-related mortality. Inherited and acquired genetic mutations as well as epigenetic aberrations are known to be… read more here.
Keywords: changes breast; breast cancer; cancer; genetic epigenetic ... See more keywords
Systemic review of genetic and epigenetic factors underlying differential toxicity to environmental lead (Pb) exposure
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-022-19333-5
Abstract: Lead (Pb) poisoning is a major public health concern in environmental justice communities of the USA and in many developing countries. There is no identified safety threshold for lead in blood, as low-level Pb exposures… read more here.
Keywords: review; health; exposure; toxicity ... See more keywords
Genetic and epigenetic alterations in meningiomas
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2017.05.002
Abstract: Meningiomas originate from the arachnoid layer of the meninges and divided histologically into three grades: benign (grade I), atypical (grade II), and malignant meningiomas (grade III). Genetic alterations in grade I meningiomas include frequent deletions… read more here.
Keywords: grade meningiomas; alterations meningiomas; meningiomas; genetic epigenetic ... See more keywords
Genetic and epigenetic alterations in the tumour, tumour margins, and normal buccal mucosa of patients with oral cancer.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of oral and maxillofacial surgery"
DOI: 10.1016/j.ijom.2018.01.020
Abstract: Despite adequate surgical resection, oral squamous cell carcinoma (OSCC) shows a high rate of recurrence and metastasis, which could be explained by the presence of molecular alterations in seemingly normal tumour margins and the entire… read more here.
Keywords: tumour margins; unaffected oral; mucosa; genetic epigenetic ... See more keywords
Combining genetic and epigenetic parameters of the serotonin transporter gene in obsessive-compulsive disorder.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2017.10.010
Abstract: While genetic variants have been reported to be associated with obsessive-compulsive disorder (OCD), the small effect sizes suggest that epigenetic mechanisms such as DNA methylation may also be relevant. The serotonin transporter (SLC6A4) gene has… read more here.
Keywords: serotonin transporter; compulsive disorder; obsessive compulsive; disorder ... See more keywords