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   Articles with "genetic frontotemporal" as a keyword



The CBI‐R detects early behavioural impairment in genetic frontotemporal dementia

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recommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.51544

Abstract: Behavioural dysfunction is a key feature of genetic frontotemporal dementia (FTD) but validated clinical scales measuring behaviour are lacking at present. read more here.

Keywords: early behavioural; detects early; frontotemporal dementia; genetic frontotemporal ... See more keywords

Data‐driven staging of genetic frontotemporal dementia using multi‐modal MRI

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recommendations! Published in 2022 at "Human Brain Mapping"

DOI: 10.1002/hbm.25727

Abstract: Frontotemporal dementia in genetic forms is highly heterogeneous and begins many years to prior symptom onset, complicating disease understanding and treatment development. Unifying methods to stage the disease during both the presymptomatic and symptomatic phases… read more here.

Keywords: cti; disease; data driven; dementia ... See more keywords
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Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

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recommendations! Published in 2019 at "Brain"

DOI: 10.1093/brain/awz039

Abstract: Imaging biomarkers are needed to detect early brain changes in presymptomatic carriers harbouring FTD mutations. Using arterial spin labelling-MRI, Mutsaerts, Mirza et al. identify an inverse association between cerebral perfusion in frontotemporoparietal regions and expected… read more here.

Keywords: cerebral perfusion; perfusion; presymptomatic genetic; changes presymptomatic ... See more keywords

Montreal Cognitive Assessment vs the Mini-Mental State Examination as a Screening Tool for Patients With Genetic Frontotemporal Dementia

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recommendations! Published in 2025 at "Neurology"

DOI: 10.1212/wnl.0000000000213401

Abstract: Background and Objectives With upcoming clinical trials targeting preclinical stages of genetic frontotemporal dementia (FTD), early detection through cognitive screening is crucial. The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) have potential as… read more here.

Keywords: frontotemporal dementia; mental state; moca; mmse ... See more keywords

Cerebrospinal Fluid Biomarker Profile in TDP-43-Related Genetic Frontotemporal Dementia

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recommendations! Published in 2022 at "Journal of Personalized Medicine"

DOI: 10.3390/jpm12101747

Abstract: Cerebrospinal fluid (CSF) biomarkers, namely total tau, phospho-tau and amyloid beta peptides, have received much attention specifically regarding Alzheimer’s disease (AD), since they can detect the biochemical fingerprint of AD and serve as a diagnostic… read more here.

Keywords: cerebrospinal fluid; frontotemporal dementia; genetic frontotemporal; medicine ... See more keywords