The CBI‐R detects early behavioural impairment in genetic frontotemporal dementia
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51544
Abstract: Behavioural dysfunction is a key feature of genetic frontotemporal dementia (FTD) but validated clinical scales measuring behaviour are lacking at present. read more here.
Keywords: early behavioural; detects early; frontotemporal dementia; genetic frontotemporal ... See more keywords
Data‐driven staging of genetic frontotemporal dementia using multi‐modal MRI
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.25727
Abstract: Frontotemporal dementia in genetic forms is highly heterogeneous and begins many years to prior symptom onset, complicating disease understanding and treatment development. Unifying methods to stage the disease during both the presymptomatic and symptomatic phases… read more here.
Keywords: cti; disease; data driven; dementia ... See more keywords
Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study
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DOI: 10.1093/brain/awz039
Abstract: Imaging biomarkers are needed to detect early brain changes in presymptomatic carriers harbouring FTD mutations. Using arterial spin labelling-MRI, Mutsaerts, Mirza et al. identify an inverse association between cerebral perfusion in frontotemporoparietal regions and expected… read more here.
Keywords: cerebral perfusion; perfusion; presymptomatic genetic; changes presymptomatic ... See more keywords
Cerebrospinal Fluid Biomarker Profile in TDP-43-Related Genetic Frontotemporal Dementia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12101747
Abstract: Cerebrospinal fluid (CSF) biomarkers, namely total tau, phospho-tau and amyloid beta peptides, have received much attention specifically regarding Alzheimer’s disease (AD), since they can detect the biochemical fingerprint of AD and serve as a diagnostic… read more here.
Keywords: cerebrospinal fluid; frontotemporal dementia; genetic frontotemporal; medicine ... See more keywords