Can Kidney Organoid Xenografts Accelerate Therapeutic Development for Genetic Kidney Disorders?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2022080862
Abstract: A number of genetic kidney diseases can now be replicated experimentally, using kidney organoids generated from human pluripotent stem cells. This methodology holds great potential for drug discovery. Under in vitro conditions, however, kidney organoids… read more here.
Keywords: organoid xenografts; methodology; genetic kidney; kidney organoid ... See more keywords
Combined Preimplantation Genetic Testing for Genetic Kidney Disease: Genetic Risk Identification, Assisted Reproductive Cycle, and Pregnancy Outcome Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.936578
Abstract: Background Genetic kidney disease is a major cause of morbidity and mortality in neonates and end-stage renal disease (ESRD) in children and adolescents. Genetic diagnosis provides key information for early identification of congenital kidney disease… read more here.
Keywords: preimplantation genetic; genetic kidney; disease; kidney ... See more keywords