Articles with "genetic lesions" as a keyword



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Genetic lesions and targeted therapy in Hodgkin lymphoma

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Published in 2023 at "Therapeutic Advances in Hematology"

DOI: 10.1177/20406207221149245

Abstract: Hodgkin lymphoma is a special type of lymphoma in which tumor cells frequently undergo multiple genetic lesions that are associated with accompanying pathway abnormalities. These pathway abnormalities are dominated by active signaling pathways, such as… read more here.

Keywords: hodgkin lymphoma; lymphoma; genetic lesions; lesions targeted ... See more keywords
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Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma.

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Published in 2022 at "Blood"

DOI: 10.1182/blood.2022015926

Abstract: Unique molecular vulnerabilities have been identified in the aggressive MCD/C5 genetic subclass of diffuse large B cell lymphoma (DLBCL). However, the pre-malignant cell-of-origin exhibiting MCD-like dependencies remains elusive. In this study, we examined animals carrying… read more here.

Keywords: cell; lymphoma; hallmark genetic; genetic lesions ... See more keywords
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Population structure, case clusters, and genetic lesions associated with Canadian Salmonella 4,[5],12:i:- isolates

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Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0249079

Abstract: Monophasic Salmonella 4,[5]:12:i:- are a major public health problem because they are one of the top five Salmonella serotypes isolated from clinical cases globally and because they can carry resistance to multiple antibiotics. A total… read more here.

Keywords: genetic lesions; salmonella; population structure; case clusters ... See more keywords