Novel genetic loci associated with hippocampal volume
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms13624
Abstract: The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the… read more here.
Keywords: associated hippocampal; novel genetic; volume; hippocampal volume ... See more keywords
Genome-wide meta-analysis revealed several genetic loci associated with serum uric acid levels in Korean population: an analysis of Korea Biobank data.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of human genetics"
DOI: 10.1038/s10038-021-00991-1
Abstract: The serum uric acid (SUA) level is an important determinant of gout, hypertension, metabolic syndrome, and cardiovascular disease. Although previous genome-wide studies have identified multiple genetic variants associated with SUA, most genetic analyses have focused… read more here.
Keywords: genome wide; analysis; genetic loci; korean population ... See more keywords
Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/s41380-018-0040-6
Abstract: Variance in IQ is associated with a wide range of health outcomes, and 1% of the population are affected by intellectual disability. Despite a century of research, the fundamental neural underpinnings of intelligence remain unclear.… read more here.
Keywords: intelligence; associated intelligence; genetic loci; annotation genetic ... See more keywords
Discovery of new genetic loci for male sexual orientation in Han population
Sign Up to like & getrecommendations! Published in 2021 at "Cell Discovery"
DOI: 10.1038/s41421-021-00341-7
Abstract: Epidemiological studies have demonstrated that the genetic factors partly influence the development of same-sex sexual behavior, but most genetic studies have focused on people of primarily European ancestry, potentially missing important biological insights. Here, we… read more here.
Keywords: meta; male sexual; genetic loci; sexual orientation ... See more keywords
Resolving phylogenetic relationships of Delphacini and Tropidocephalini (Hemiptera: Delphacidae: Delphacinae) as inferred from four genetic loci
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03624-w
Abstract: This paper explores the phylogeny of the delphacid subfamily Delphacinae based on nuclear ribosomal and mitochondrial DNA sequences of four genetic loci (16S rDNA, 28S rDNA, Cytochrome oxidase I and Cytochrome b). Maximum likelihood and… read more here.
Keywords: delphacinae; genetic loci; tropidocephalini; four genetic ... See more keywords
Lipid metabolism: from genetic loci to functional understanding.
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Lipidology"
DOI: 10.1097/mol.0000000000000380
Abstract: DOI:10.1097/MOL.0000000000000380 Large-scale genome-wide association studies (GWAS) have led to thediscoveryof a multitudeof genetic loci related to plasma lipid levels [1,2]. A significant number of these loci harbor genes for which there has been no prior… read more here.
Keywords: metabolism; plasma hdl; lipid metabolism; genetic loci ... See more keywords
Identification of genetic loci associated with crude protein and mineral concentrations in alfalfa (Medicago sativa) using association mapping
Sign Up to like & getrecommendations! Published in 2017 at "BMC Plant Biology"
DOI: 10.1186/s12870-017-1047-x
Abstract: BackgroundAlfalfa (Medicago sativa) is one of the most important legume forage species in China and many other countries of the world. It provides a quality source of proteins and minerals to animals. Genetic underpinnings for… read more here.
Keywords: identification genetic; medicago sativa; genetic loci; association mapping ... See more keywords
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Medicine"
DOI: 10.1371/journal.pmed.1002654
Abstract: Background Type 2 diabetes (T2D) is a heterogeneous disease for which (1) disease-causing pathways are incompletely understood and (2) subclassification may improve patient management. Unlike other biomarkers, germline genetic markers do not change with disease… read more here.
Keywords: analysis; t2d; genetic loci; disease ... See more keywords
Identification of novel genetic loci for osteoporosis and/or rheumatoid arthritis using cFDR approach
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183842
Abstract: There are co-morbidity between osteoporosis (OP) and rheumatoid arthritis (RA). Some genetic risk factors have been identified for these two phenotypes respectively in previous research; however, they accounted for only a small portion of the… read more here.
Keywords: loci; genetic loci; osteoporosis rheumatoid; cfdr approach ... See more keywords
Genetic Loci in Phospholipase C-Like 1 (PLCL1) are Protective Factors for Allergic Rhinitis in Han Population of Northern Shaanxi, China
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s372314
Abstract: Background Allergic rhinitis (AR) is a common allergic disease in otolaryngology. Its pathogenesis is still unclear. PLC1 plays a key role in calcium homeostasis and immune response, which is potentially related to AR. We aimed… read more here.
Keywords: allele plcl1; protective factors; han population; plcl1 ... See more keywords
Risk Genetic Variants (IL-10) for Osteoporosis in Han Population from Northwest China
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s396914
Abstract: Background Osteoporosis (OP) is a common metabolic bone disease characterized by loss of bone mass. IL-10 is considered to be a powerful immune and inflammatory suppressor. This study aimed to assess association between genetic loci… read more here.
Keywords: risk genetic; osteoporosis; risk; analysis ... See more keywords