Articles with "genetic manipulations" as a keyword



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Real-Time Genetic Manipulations of the Cytokinin Pathway: A Tool for Laboratory and Field Studies.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-6831-2_10

Abstract: Although many established tools for cytokinin (CK) pathway manipulations are well suitable for the analysis of molecular interactions, their use on a whole plant scale is often limited by the induction of severe developmental defects.… read more here.

Keywords: real time; time genetic; field; laboratory ... See more keywords
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Genetic manipulations of AMPA glutamate receptors in hippocampal synaptic plasticity

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Published in 2021 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2021.108630

Abstract: Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are the principal mediators of fast excitatory synaptic transmission and they are required for various forms of synaptic plasticity, including long-term potentiation (LTP) and depression (LTD), which are key mechanisms of… read more here.

Keywords: ampa glutamate; manipulations ampa; synaptic plasticity; glutamate receptors ... See more keywords
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Naturally Selected CD7 CAR-T Therapy without Genetic Manipulations for T-ALL/LBL: First-in-human Phase I Clinical Trial.

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Published in 2022 at "Blood"

DOI: 10.1182/blood.2021014498

Abstract: Derivation of CD7-targeted chimeric antigen receptor (7CAR) T cells often requires genetic manipulations to ablate the CD7 gene or block CD7 cell surface expression. Our novel approach deriving naturally selected 7CAR-T cells (NS7CAR) from bulk… read more here.

Keywords: 7car cells; genetic manipulations; cd7; trial ... See more keywords