Non canonical genetic material.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2018.12.001
Abstract: To increase the scope of natural biosystem, nucleic acids have been intensively modified. One direction includes the development of a synthetic alternative to the native DNA and RNA, denoted Xenobiotic nucleic acids (XNAs) that are… read more here.
Keywords: genetic material; non canonical; base; canonical genetic ... See more keywords
A tale of topoisomerases and the knotty genetic material in the backdrop of Plasmodium biology
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DOI: 10.1042/bsr20212847
Abstract: Abstract The untangling or overwinding of genetic material is an inevitable part of DNA replication, repair, recombination, and transcription. Topoisomerases belong to a conserved enzyme family that amends DNA topology during various processes of DNA… read more here.
Keywords: dna; genetic material; plasmodium; topoisomerase ... See more keywords
Development and Validation of an Anion-Exchange High-Performance Liquid Chromatography Method for Analysis of Empty Capsids and Capsids Encapsidating Genetic Material in a Purified Preparation of Recombinant Adeno-Associated Virus Serotype 5.
Sign Up to like & getrecommendations! Published in 2021 at "Human gene therapy"
DOI: 10.1089/hum.2020.317
Abstract: The development of various manufacturing platforms and analytical technologies has substantially contributed to successfully translating the recombinant adeno-associated viral vector from the lab to the clinic. The active deployment of these analytical technologies for process… read more here.
Keywords: genetic material; recombinant adeno; method; adeno associated ... See more keywords
Recombination and gene loss occur simultaneously during bacterial horizontal gene transfer
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DOI: 10.1371/journal.pone.0227987
Abstract: Bacteria can acquire new genes by incorporating environmental DNA into their genomes, yet genome sizes stay relatively constant. In nature, gene acquisition is a rare event so it is difficult to observe. However, the Caulobacter… read more here.
Keywords: genetic material; transfer; gene transfer; recombination ... See more keywords
Sensitivity and detection of chikungunya viral genetic material using several PCR-based approaches.
Sign Up to like & getrecommendations! Published in 2017 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0403-2016
Abstract: INTRODUCTION: Chikungunya fever is a condition resulting from infection by chikungunya virus (CHIKV), an Aedes sp.-transmitted virus. This disease has been diagnosed in thousands of cases in the Americas, particularly in Brazil, in recent years,… read more here.
Keywords: genetic material; detection; sensitivity; pcr ... See more keywords
Photochemical Internalization of siRNA for Cancer Therapy
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DOI: 10.3390/cancers14153597
Abstract: Simple Summary The objective of this review is to focus on the different nanovectors capable of transporting genetic material such as small-interfering RNA (siRNA) in order to block the expression of genes responsible for the… read more here.
Keywords: genetic material; therapy; sirna; photochemical internalization ... See more keywords
Managing Viral Emerging Infectious Diseases via Current and Future Molecular Diagnostics
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13081421
Abstract: Emerging viral infectious diseases have been a constant threat to global public health in recent times. In managing these diseases, molecular diagnostics has played a critical role. Molecular diagnostics involves the use of various technologies… read more here.
Keywords: viral infectious; infectious diseases; crispr cas; genetic material ... See more keywords
Novel Psychoactive Phenethylamines: Impact on Genetic Material
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21249616
Abstract: Psychedelic and stimulating phenethylamines belong to the family of new psychoactive substances (NPS). The acute toxicity framework has begun to be investigated, while studies showing genotoxic potential are very limited or not available. Therefore, in… read more here.
Keywords: genetic material; psychoactive phenethylamines; phenethylamines impact; genotoxicity ... See more keywords
The Process of Binding and Releasing of Genetic Material from Lipoplexes Based on Trimeric Surfactants and Phospholipids
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22147744
Abstract: Nonviral vectors for gene therapy such as lipoplexes are characterized by low toxicity, high biocompatibility, and good transfection efficiency. Specifically, lipoplexes based on polymeric surfactants and phospholipids have great potential as gene carriers due to… read more here.
Keywords: genetic material; based trimeric; lipoplexes based; trimeric surfactants ... See more keywords
Non-Invasive Preimplantation Genetic Testing for Aneuploidy and the Mystery of Genetic Material: A Review Article
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073568
Abstract: This review focuses on recent findings in the preimplantation genetic testing (PGT) of embryos. Different preimplantation genetic tests are presented along with different genetic materials and their analysis. Original material concerning preimplantation genetic testing for… read more here.
Keywords: preimplantation genetic; genetic material; pgt; genetic testing ... See more keywords
Lactoferrin as a Human Genome “Guardian”—An Overall Point of View
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095248
Abstract: Structural abnormalities causing DNA modifications of the ethene and propanoadducts can lead to mutations and permanent damage to human genetic material. Such changes may cause premature aging and cell degeneration and death as well as… read more here.
Keywords: human genome; genetic material; overall point; guardian overall ... See more keywords