Computational Re-design of Synthetic Genetic Oscillators for Independent Amplitude and Frequency Modulation.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.03.013
Abstract: To perform well in biotechnology applications, synthetic genetic oscillators must be engineered to allow independent modulation of amplitude and period. This need is currently unmet. Here, we demonstrate computationally how two classic genetic oscillators, the… read more here.
Keywords: computational design; modulation; genetic oscillators; design synthetic ... See more keywords
Chemical event chain model of coupled genetic oscillators.
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review E"
DOI: 10.1103/physreve.97.032409
Abstract: We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states by their frequency,… read more here.
Keywords: chemical event; event chain; coupled genetic; model ... See more keywords