GPSAdb: a comprehensive web resource for interactive exploration of genetic perturbation RNA-seq datasets
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1066
Abstract: Abstract Gene knock-out/down methods are commonly used to explore the functions of genes of interest, but a database that systematically collects perturbed data is not available currently. Manual curation of all the available human cell… read more here.
Keywords: seq datasets; rna seq; gpsadb; genetic perturbation ... See more keywords
PertOrg 1.0: a comprehensive resource of multilevel alterations induced in model organisms by in vivo genetic perturbation
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DOI: 10.1093/nar/gkac872
Abstract: Abstract Genetically modified organisms (GMOs) can be generated to model human genetic disease or plant disease resistance, and they have contributed to the exploration and understanding of gene function, physiology, disease onset and drug target… read more here.
Keywords: multilevel alterations; model organisms; pertorg; genetic perturbation ... See more keywords
Genetic Perturbation of the Starch Biosynthesis in Maize Endosperm Reveals Sugar-Responsive Gene Networks
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DOI: 10.3389/fpls.2021.800326
Abstract: In maize, starch mutants have facilitated characterization of key genes involved in endosperm starch biosynthesis such as large subunit of AGPase Shrunken2 (Sh2) and isoamylase type DBE Sugary1 (Su1). While many starch biosynthesis enzymes have… read more here.
Keywords: perturbation starch; starch; genetic perturbation; starch biosynthesis ... See more keywords