Genetic Reduction of Matrix Metalloproteinase-9 Promotes Formation of Perineuronal Nets Around Parvalbumin-Expressing Interneurons and Normalizes Auditory Cortex Responses in Developing Fmr1 Knock-Out Mice
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral Cortex"
DOI: 10.1093/cercor/bhx258
Abstract: Abnormal sensory responses associated with Fragile X Syndrome (FXS) and autism spectrum disorders include hypersensitivity and impaired habituation to repeated stimuli. Similar sensory deficits are also observed in adult Fmr1 knock-out (KO) mice and are… read more here.
Keywords: mmp; auditory cortex; genetic reduction; mice ... See more keywords
Dopamine Transporter Genetic Reduction Induces Morpho-Functional Changes in the Enteric Nervous System
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DOI: 10.3390/biomedicines9050465
Abstract: Antidopaminergic gastrointestinal prokinetics are indeed commonly used to treat gastrointestinal motility disorders, although the precise role of dopaminergic transmission in the gut is still unclear. Since dopamine transporter (DAT) is involved in several brain disorders… read more here.
Keywords: system; nervous system; genetic reduction; dopamine transporter ... See more keywords